The Nord-Trøndelag Health Study (The HUNT Study) is one of the largest health studies ever performed. It is a unique database of personal and family medical histories collected during three intensive studies. The fundamental strategy is to earn and maintain the confidence of the population we work in and with as is necessary for any successful population study. This strategy has been successful and has resulted in extraordinarily high participation rates. There is enthusiastic public and political support for HUNT and for the HUNT Research Centre. This has created a good basis for further health surveys in the county and an excellent research environment. Today, the HUNT Study is a database with information about approximately 120,000 people that integrates family data and individual data and can be linked to national health registries.