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Found 5 result(s)
The Comprehensive Epidemiologic Data Resource (CEDR) is the Department of Energy's (DOE) electronic database comprised of health studies of DOE contract workers and environmental studies of areas surrounding DOE facilities. DOE recognizes the benefits of data sharing and supports the public's right to know about worker and community health risks. CEDR provides independent researchers and the public with access to de-identified data collected since the Department's early production years. Current CEDR holdings include more than 80 studies of over 1 million workers at 31 DOE sites. Access to these data is at no cost to the user. Most of CEDR's holdings are derived from epidemiologic studies of DOE workers at many large nuclear weapons plants, such as Hanford, Los Alamos, the Oak Ridge reservation, Savannah River Site, and Rocky Flats. These studies primarily use death certificate information to identify excess deaths and patterns of disease among workers to determine what factors contribute to the risk of developing cancer and other illnesses. In addition, many of these studies have radiation exposure measurements on individual workers. CEDR is supported by the Oak Ridge Institute for Science and Education (ORISE) in Oak Ridge, Tennessee. Now a mature system in routine operational use, CEDR's modern internet-based systems respond to thousands of requests to its web server daily. With about 1,500 Internet sites pointing to CEDR's web site, CEDR is a national user facility, with a large audience for data that are not available elsewhere.
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The Cystic Fibrosis Mutation Database (CFTR1) was initiated by the Cystic Fibrosis Genetic Analysis Consortium in 1989 to increase and facilitate communications among CF researchers, and is maintained by the Cystic Fibrosis Centre at the Hospital for Sick Children in Toronto. The specific aim of the database is to provide up to date information about individual mutations in the CFTR gene. In a major upgrade in 2010, all known CFTR mutations and sequence variants have been converted to the standard nomenclature recommended by the Human Genome Variation Society.
GeneWeaver combines cross-species data and gene entity integration, scalable hierarchical analysis of user data with a community-built and curated data archive of gene sets and gene networks, and tools for data driven comparison of user-defined biological, behavioral and disease concepts. Gene Weaver allows users to integrate gene sets across species, tissue and experimental platform. It differs from conventional gene set over-representation analysis tools in that it allows users to evaluate intersections among all combinations of a collection of gene sets, including, but not limited to annotations to controlled vocabularies. There are numerous applications of this approach. Sets can be stored, shared and compared privately, among user defined groups of investigators, and across all users.
PHI-base is a web-accessible database that catalogues experimentally verified pathogenicity, virulence and effector genes from fungal, Oomycete and bacterial pathogens, which infect animal, plant, fungal and insect hosts. PHI-base is therfore an invaluable resource in the discovery of genes in medically and agronomically important pathogens, which may be potential targets for chemical intervention. In collaboration with the FRAC team, PHI-base also includes antifungal compounds and their target genes.
XNAT CENTRAL is a publicly accessible datasharing portal at Washinton University Medical School using XNAT software. XNAT provides neuroimaging data through a web interface and a customizable open source platform. XNAT facilitates data uploads and downloads for data sharing, processing and organization.