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NCBI Datasets is a continually evolving platform designed to provide easy and intuitive access to NCBI’s sequence data and metadata. NCBI Datasets is part of the NIH Comparative Genomics Resource (CGR). CGR facilitates reliable comparative genomics analyses for all eukaryotic organisms through an NCBI Toolkit and community collaboration.
IntEnz contains the recommendation of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology on the nomenclature and classification of enzyme-catalyzed reactions. Users can browse by enzyme classification or use advanced search options to search enzymes by class, subclass and sub-subclass information.
M-CSA is a database of enzyme reaction mechanisms. It provides annotation on the protein, catalytic residues, cofactors, and the reaction mechanisms of hundreds of enzymes. There are two kinds of entries in M-CSA. 'Detailed mechanism' entries are more complete and show the individual chemical steps of the mechanism as schemes with electron flow arrows. 'Catalytic Site' entries annotate the catalytic residues necessary for the reaction, but do not show the mechanism. The M-CSA (Mechanism and Catalytic Site Atlas) represents a unified resource that combines the data in both MACiE and the CSA
The Centre for the Environment, Fisheries and Aquaculture Science (Cefas), as one of the world's longest-established marine research organisations, has provided advice on the sustainable exploitation of marine resources since 1902. Today Cefas works in support of a healthy environment and a growing blue economy providing innovative solutions for the aquatic environment, biodiversity and food security. The Cefas Data Hub provides access to over 2080 metadata records, with over 5500 data sets available to download and connect to in support of commitments to Open Science through the Data Portal. Datasets available are increasingly diverse and include many legacy datasets including those from fish, shellfish and plankton surveys from the 1980's to the present day. Other increasingly international datasets made available include species migration data from tagging activities and data on habitat and sediment, ecosystem change, human activities including marine litter, otolith sampling and fish stomach contents, oceanography, acoustics, health and water quality. Data is provided under Open Government License by default where feasible.
The 1000 Genomes Project is an international collaboration to produce an extensive public catalog of human genetic variation, including SNPs and structural variants, and their haplotype contexts. This resource will support genome-wide association studies and other medical research studies. The genomes of about 2500 unidentified people from about 25 populations around the world will be sequenced using next-generation sequencing technologies. The results of the study will be freely and publicly accessible to researchers worldwide. The International Genome Sample Resource (IGSR) has been established at EMBL-EBI to continue supporting data generated by the 1000 Genomes Project, supplemented with new data and new analysis.
The DPUK Data Portal brings together records of over 2 million people in a free-to-access resource. Researchers can identify which cohorts are relevant to them, apply for access to the data and then analyse it in a secure, remote environment with a complete data linkage and analysis package.
The MEROPS database is an information resource for peptidases (also termed proteases, proteinases and proteolytic enzymes) and the proteins that inhibit them.
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KEGG is a database resource for understanding high-level functions and utilities of the biological system, such as the cell, the organism and the ecosystem, from molecular-level information, especially large-scale molecular datasets generated by genome sequencing and other high-throughput experimental technologies