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Found 4 result(s)

International Mouse Phenotyping Consortium

IMPC

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The IMPC is a confederation of international mouse phenotyping projects working towards the agreed goals of the consortium: To undertake the phenotyping of 20,000 mouse mutants over a ten year period, providing the first functional annotation of a mammalian genome. Maintain and expand a world-wide consortium of institutions with capacity and expertise to produce germ line transmission of targeted knockout mutations in embryonic stem cells for 20,000 known and predicted mouse genes. Test each mutant mouse line through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease. Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems; Maintain and expand collaborative “networks” with specialist phenotyping consortia or laboratories, providing standardized secondary level phenotyping that enriches the primary dataset, and end-user, project specific tertiary level phenotyping that adds value to the mammalian gene functional annotation and fosters hypothesis driven research; and Provide a centralized data centre and portal for free, unrestricted access to primary and secondary data by the scientific community, promoting sharing of data, genotype-phenotype annotation, standard operating protocols, and the development of open source data analysis tools. Members of the IMPC may include research centers, funding organizations and corporations.

ScienceDB

Science Data Bank

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Science Data Bank is an open generalist data repository developed and maintained by the Chinese Academy of Sciences Computing and Network Information Center (CNIC). It promotes the publication and reuse of scientific data. Researchers and journal publishers can use it to store, manage and share science data.

National Marine Data and Information Service

NMDIS

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As the third center for oceanography of the World Data Center following WDC-A of the United States and WDC-B of Russia, WDC-D for oceanography boasts long-term and stable sources of domestic marine basic data. The State Oceanic Administration now has long-term observations obtained from the fixed coastal ocean stations, offshore and oceanic research vessels, moored and drifting buoys. More and more marine data have been available from the Chinese-foreign marine cooperative surveys, analysis and measurement of laboratory samples, reception by the satellite ground station, aerial telemeter and remote sensing, the GOOS program and global ships of opportunity reports, etc; More marine data are being and will be obtained from the ongoing “863” program, one of the state key projects during the Ninth Five-year plan and the seasat No 1 which is scheduled to be launched next year. Through many years’ effort, the WDC-D for oceanography has established formal relationship of marine data exchange with over 130 marine institutions in more than 60 countries in the world and is maintaining a close relationship of data exchange with over 30 major national oceanographic data centers. The established China Oceanic Information Network has joined the international marine data exchange system via Internet. Through these channels, a large amount data have been acquired of through international exchange, which, plus the marine data collected at home for many years, has brought the WDC-D for Oceanography over 100 years’ global marine data with a total data amounting to more than 10 billion bytes. In the meantime, a vast amount of work has been done in the standardized and normalized processing and management of the data, and a series of national and professional standards have been formulated and implemented successively. Moreover, appropriate standards and norms are being formulated as required.

China National GeneBank DataBase

国家基因库生命大数据平台

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The China National GeneBank database (CNGBdb) is a unified platform for biological big data sharing and application services. CNGBdb has now integrated a large amount of internal and external biological data from resources such as CNGB, NCBI, and the EBI. There are several sub-databases in CNGBdb, including literature, variation, gene, genome, protein, sequence, organism, project, sample, experiment, run, and assembly. Based on underlying big data and cloud computing technologies, it provides various data services, including archive, analysis, knowledge search, and management authorization of biological data. CNGBdb adopts data structures and standards of international omics, health, and medicine, such as The International Nucleotide Sequence Database Collaboration (INSDC), The Global Alliance for Genomics and Health GA4GH (GA4GH), Global Genome Biodiversity Network (GGBN), American College of Medical Genetics and Genomics (ACMG), and constructs standardized data and structures with wide compatibility. All public data and services provided by CNGBdb are freely available to all users worldwide. CNGB Sequence Archive (CNSA) is the bionomics data repository of CNGBdb. CNGB Sequence Archive (CNSA) is a convenient and efficient archiving system of multi-omics data in life science, which provides archiving services for raw sequencing reads and further analyzed results. CNSA follows the international data standards for omics data, and supports online and batch submission of multiple data types such as Project, Sample, Experiment/Run, Assembly, Variation, Metabolism, Single cell, and Sequence. Moreover, CNSA has achieved the correlation of sample entities, sample information, and analyzed data on some projects. Its data submission service can be used as a supplement to the literature publishing process to support early data sharing.CNGB Sequence Archive (CNSA) is a convenient and efficient archiving system of multi-omics data in the life science of CNGBdb, which provides archiving services for raw sequencing reads and further analyzed results. CNSA follows the international data standards for omics data, and supports online and batch submission of multiple data types such as Project, Sample, Experiment/Run, Assembly, Variation, Metabolism, Single cell, Sequence. Its data submission service can be used as a supplement to the literature publishing process to support early data sharing.