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Found 244 result(s)
STRING is a database of known and predicted protein interactions. The interactions include direct (physical) and indirect (functional) associations; they are derived from four sources: - Genomic Context - High-throughput Experiments - (Conserved) Coexpression - Previous Knowledge STRING quantitatively integrates interaction data from these sources for a large number of organisms, and transfers information between these organisms where applicable.
The National Deep Submergence Facility (NDSF) operates the Human Occupied Vehicle (HOV) Alvin, the Remote Operated Vehicle (ROV) Jason 2, and the Autonomous Underwater Vehicle (AUV) Sentry. Data acquired with these platforms is provided both to the science party on each expedition, and to the Woods Hole Oceanographic Institution (WHOI) Data Library.
The IMEx consortium is an international collaboration between a group of major public interaction data providers who have agreed to share curation effort and develop and work to a single set of curation rules when capturing data from both directly deposited interaction data or from publications in peer-reviewed journals, capture full details of an interaction in a “deep” curation model, perform a complete curation of all protein-protein interactions experimentally demonstrated within a publication, make these interaction available in a single search interface on a common website, provide the data in standards compliant download formats, make all IMEx records freely accessible under the Creative Commons Attribution License
The Space Physics Data Facility (SPDF) leads in the design and implementation of unique multi-mission and multi-disciplinary data services and software to strategically advance NASA's solar-terrestrial program, to extend our science understanding of the structure, physics and dynamics of the Heliosphere of our Sun and to support the science missions of NASA's Heliophysics Great Observatory. Major SPDF efforts include multi-mission data services such as Heliophysics Data Portal (formerly VSPO), CDAWeb and CDAWeb Inside IDL,and OMNIWeb Plus (including COHOWeb, ATMOWeb, HelioWeb and CGM) , science planning and orbit services such as SSCWeb, data tools such as the CDF software and tools, and a range of other science and technology research efforts. The staff supporting SPDF includes scientists and information technology experts.
A collection of data at Agency for Healthcare Research and Quality (AHRQ) supporting research that helps people make more informed decisions and improves the quality of health care services. The portal contains U.S.Health Information Knowledgebase (USHIK) and Systematic Review Data Repository (SRDR) and other sources concerning cost, quality, accesibility and evaluation of healthcare and medical insurance.
CLARIN is a European Research Infrastructure for the Humanities and Social Sciences, focusing on language resources (data and tools). It is being implemented and constantly improved at leading institutions in a large and growing number of European countries, aiming at improving Europe's multi-linguality competence. CLARIN provides several services, such as access to language data and tools to analyze data, and offers to deposit research data, as well as direct access to knowledge about relevant topics in relation to (research on and with) language resources. The main tool is the 'Virtual Language Observatory' providing metadata and access to the different national CLARIN centers and their data.
The European Bioinformatics Institute (EBI) has a long-standing mission to collect, organise and make available databases for biomolecular science. It makes available a collection of databases along with tools to search, download and analyse their content. These databases include DNA and protein sequences and structures, genome annotation, gene expression information, molecular interactions and pathways. Connected to these are linking and descriptive data resources such as protein motifs, ontologies and many others. In many of these efforts, the EBI is a European node in global data-sharing agreements involving, for example, the USA and Japan.
Chempound is a new generation repository architecture based on RDF, semantic dictionaries and linked data. It has been developed to hold any type of chemical object expressible in CML and is exemplified by crystallographic experiments and computational chemistry calculations. In both examples, the repository can hold >50k entries which can be searched by SPARQL endpoints and pre-indexing of key fields. The Chempound architecture is general and adaptable to other fields of data-rich science.
This Animal Quantitative Trait Loci (QTL) database (Animal QTLdb) is designed to house all publicly available QTL and trait mapping data (i.e. trait and genome location association data; collectively called "QTL data" on this site) on livestock animal species for easily locating and making comparisons within and between species. New database tools are continuely added to align the QTL and association data to other types of genome information, such as annotated genes, RH / SNP markers, and human genome maps. Besides the QTL data from species listed below, the QTLdb is open to house QTL/association date from other animal species where feasible. Note that the JAS along with other journals, now require that new QTL/association data be entered into a QTL database as part of their publication requirements.
The Global Hydrology Resource Center (GHRC) provides both historical and current Earth science data, information, and products from satellite, airborne, and surface-based instruments. GHRC acquires basic data streams and produces derived products from many instruments spread across a variety of instrument platforms.
The National Archives and Records Administration (NARA) is the nation's record keeper. Of all documents and materials created in the course of business conducted by the United States Federal government, only 1%-3% are so important for legal or historical reasons that they are kept by us forever. Those valuable records are preserved and are available to you, whether you want to see if they contain clues about your family’s history, need to prove a veteran’s military service, or are researching an historical topic that interests you.
! The National Climatic Data Center has merged into the National Centers for Environmental Information (NCEI). NOAA's National Climatic Data Center (NCDC) is responsible for preserving, monitoring, assessing, and providing public access to the Nation's treasure of climate and historical weather data and information.
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JASPAR is the leading open-access database of matrix profiles describing the DNA-binding patterns of transcription factors and other proteins interacting with DNA in a sequence-specific manner.
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prometheus is a digital image archive for Art and Cultural Sciences. prometheus enables the convenient search for images on a common user interface within different image archives, variable databases from institutes, research facilities and museums.
The Abacus Dataverse Network is the research data repository of the British Columbia Research Libraries' Data Services, a collaboration involving the Data Libraries at Simon Fraser University (SFU), the University of British Columbia (UBC), the University of Northern British Columbia (UNBC) and the University of Victoria (UVic).
The Northern California Earthquake Data Center (NCEDC) is a permanent archive and distribution center primarily for multiple types of digital data relating to earthquakes in central and northern California. The NCEDC is located at the Berkeley Seismological Laboratory, and has been accessible to users via the Internet since mid-1992. The NCEDC was formed as a joint project of the Berkeley Seismological Laboratory (BSL) and the U.S. Geological Survey (USGS) at Menlo Park in 1991, and current USGS funding is provided under a cooperative agreement for seismic network operations.
The Ontology Lookup Service (OLS) is a repository for biomedical ontologies that aims to provide a single point of access to the latest ontology versions. The user can browse the ontologies through the website as well as programmatically via the OLS API. The OLS provides a web service interface to query multiple ontologies from a single location with a unified output format.The OLS can integrate any ontology available in the Open Biomedical Ontology (OBO) format. The OLS is an open source project hosted on Google Code.
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GBIF is an international organisation that is working to make the world's biodiversity data accessible everywhere in the world. GBIF and its many partners work to mobilize the data, and to improve search mechanisms, data and metadata standards, web services, and the other components of an Internet-based information infrastructure for biodiversity. GBIF makes available data that are shared by hundreds of data publishers from around the world. These data are shared according to the GBIF Data Use Agreement, which includes the provision that users of any data accessed through or retrieved via the GBIF Portal will always give credit to the original data publishers.
AmoebaDB belongs to the EuPathDB family of databases and is an integrated genomic and functional genomic database for Entamoeba and Acanthamoeba parasites. In its first iteration (released in early 2010), AmoebaDB contains the genomes of three Entamoeba species (see below). AmoebaDB integrates whole genome sequence and annotation and will rapidly expand to include experimental data and environmental isolate sequences provided by community researchers . The database includes supplemental bioinformatics analyses and a web interface for data-mining.
OrthoMCL is a genome-scale algorithm for grouping orthologous protein sequences. It provides not only groups shared by two or more species/genomes, but also groups representing species-specific gene expansion families. So it serves as an important utility for automated eukaryotic genome annotation. OrthoMCL starts with reciprocal best hits within each genome as potential in-paralog/recent paralog pairs and reciprocal best hits across any two genomes as potential ortholog pairs. Related proteins are interlinked in a similarity graph. Then MCL (Markov Clustering algorithm,Van Dongen 2000; www.micans.org/mcl) is invoked to split mega-clusters. This process is analogous to the manual review in COG construction. MCL clustering is based on weights between each pair of proteins, so to correct for differences in evolutionary distance the weights are normalized before running MCL.
Online materials database (known as PAULING FILE project) with nearly 2 million entries: physical properties, crystal structures, phase diagrams, available via API, ready for modern data-intensive applications. The source of these entries are about 300,000 peer-reviewed publications in materials science, processed during the last 16 years by an international team of PhD editors. The results are presented online with a quick search interface. The basic access is provided for free.
The Expression Atlas provides information on gene expression patterns under different biological conditions such as a gene knock out, a plant treated with a compound, or in a particular organism part or cell. It includes both microarray and RNA-seq data. The data is re-analysed in-house to detect interesting expression patterns under the conditions of the original experiment. There are two components to the Expression Atlas, the Baseline Atlas and the Differential Atlas. The Baseline Atlas displays information about which gene products are present (and at what abundance) in "normal" conditions (e.g. tissue, cell type). It aims to answer questions such as "which genes are specifically expressed in human kidney?". This component of the Expression Atlas consists of highly-curated and quality-checked RNA-seq experiments from ArrayExpress. It has data for many different animal and plant species. New experiments are added as they become available. The Differential Atlas allows users to identify genes that are up- or down-regulated in a wide variety of different experimental conditions such as yeast mutants, cadmium treated plants, cystic fibrosis or the effect on gene expression of mind-body practice. Both microarray and RNA-seq experiments are included in the Differential Atlas. Experiments are selected from ArrayExpress and groups of samples are manually identified for comparison e.g. those with wild type genotype compared to those with a gene knock out. Each experiment is processed through our in-house differential expression statistical analysis pipeline to identify genes with a high probability of differential expression.
OpenTopography facilitates community access to high-resolution, Earth science-oriented, topography data, and related tools and resources. The OpenTopography Facility is based at the San Diego Supercomputer Center at the University of California, San Diego and is operated in collaboration with colleagues in the School of Earth and Space Exploration at Arizona State University. Core operational support for OpenTopography comes from the National Science Foundation Earth Sciences: Instrumentation and Facilities Program (EAR/IF) and the Office of Cyberinfrastructure. In addition, we receive funding from the NSF and NASA to support various OpenTopography related research and development activities.
The CiardRING is a global directory of web-based information services and datasets for agricultural research for development (ARD). It is the principal tool created through the CIARD initiative to allow information providers to register their services and datasets in various categories and so facilitate the discovery of sources of agriculture-related information across the world. The RING aims to provide an infrastructure to improve the accessibility of the outputs of agricultural research and of information relevant to agriculture.