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Found 67 result(s)

World Ocean Database

WOD

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The World Ocean Database (WOD) is a collection of scientifically quality-controlled ocean profile and plankton data that includes measurements of temperature, salinity, oxygen, phosphate, nitrate, silicate, chlorophyll, alkalinity, pH, pCO2, TCO2, Tritium, Δ13Carbon, Δ14Carbon, Δ18Oxygen, Freon, Helium, Δ3Helium, Neon, and plankton. WOD contains all data of "World Data Service Oceanography" (WDS-Oceanography).

Expressed Sequence Tags database

dbEST

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dbEST is a division of GenBank that contains sequence data and other information on "single-pass" cDNA sequences, or "Expressed Sequence Tags", from a number of organisms. Expressed Sequence Tags (ESTs) are short (usually about 300-500 bp), single-pass sequence reads from mRNA (cDNA). Typically they are produced in large batches. They represent a snapshot of genes expressed in a given tissue and/or at a given developmental stage. They are tags (some coding, others not) of expression for a given cDNA library. Most EST projects develop large numbers of sequences. These are commonly submitted to GenBank and dbEST as batches of dozens to thousands of entries, with a great deal of redundancy in the citation, submitter and library information. To improve the efficiency of the submission process for this type of data, we have designed a special streamlined submission process and data format. dbEST also includes sequences that are longer than the traditional ESTs, or are produced as single sequences or in small batches. Among these sequences are products of differential display experiments and RACE experiments. The thing that these sequences have in common with traditional ESTs, regardless of length, quality, or quantity, is that there is little information that can be annotated in the record. If a sequence is later characterized and annotated with biological features such as a coding region, 5'UTR, or 3'UTR, it should be submitted through the regular GenBank submissions procedure (via BankIt or Sequin), even if part of the sequence is already in dbEST. dbEST is reserved for single-pass reads. Assembled sequences should not be submitted to dbEST. GenBank will accept assembled EST submissions for the forthcoming TSA (Transcriptome Shotgun Assembly) division. The individual reads which make up the assembly should be submitted to dbEST, the Trace archive or the Short Read Archive (SRA) prior to the submission of the assemblies.

Expression Atlas

Gene Expression Atlas

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The Expression Atlas provides information on gene expression patterns under different biological conditions such as a gene knock out, a plant treated with a compound, or in a particular organism part or cell. It includes both microarray and RNA-seq data. The data is re-analysed in-house to detect interesting expression patterns under the conditions of the original experiment. There are two components to the Expression Atlas, the Baseline Atlas and the Differential Atlas. The Baseline Atlas displays information about which gene products are present (and at what abundance) in "normal" conditions (e.g. tissue, cell type). It aims to answer questions such as "which genes are specifically expressed in human kidney?". This component of the Expression Atlas consists of highly-curated and quality-checked RNA-seq experiments from ArrayExpress. It has data for many different animal and plant species. New experiments are added as they become available. The Differential Atlas allows users to identify genes that are up- or down-regulated in a wide variety of different experimental conditions such as yeast mutants, cadmium treated plants, cystic fibrosis or the effect on gene expression of mind-body practice. Both microarray and RNA-seq experiments are included in the Differential Atlas. Experiments are selected from ArrayExpress and groups of samples are manually identified for comparison e.g. those with wild type genotype compared to those with a gene knock out. Each experiment is processed through our in-house differential expression statistical analysis pipeline to identify genes with a high probability of differential expression.

GHRC

Global Hydrology Resource Center

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The Global Hydrology Resource Center (GHRC) provides both historical and current Earth science data, information, and products from satellite, airborne, and surface-based instruments. GHRC acquires basic data streams and produces derived products from many instruments spread across a variety of instrument platforms.

Barbara A. Mikulski Archive for Space Telescopes

MAST

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The Mikulski Archive for Space Telescopes (MAST) is a NASA funded project to support and provide to the astronomical community a variety of astronomical data archives, with the primary focus on scientifically related data sets in the optical, ultraviolet, and near-infrared parts of the spectrum. MAST is located at the Space Telescope Science Institute (STScI).

IntAct

IntAct Molecular Interaction Database

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IntAct provides a freely available, open source database system and analysis tools for molecular interaction data. All interactions are derived from literature curation or direct user submissions and are freely available.

The Universal Protein Resource

UniProt

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The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc).

AceView

AceView genes

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AceView provides a curated, comprehensive and non-redundant sequence representation of all public mRNA sequences (mRNAs from GenBank or RefSeq, and single pass cDNA sequences from dbEST and Trace). These experimental cDNA sequences are first co-aligned on the genome then clustered into a minimal number of alternative transcript variants and grouped into genes. Using exhaustively and with high quality standards the available cDNA sequences evidences the beauty and complexity of mammals’ transcriptome, and the relative simplicity of the nematode and plant transcriptomes. Genes are classified according to their inferred coding potential; many presumably non-coding genes are discovered. Genes are named by Entrez Gene names when available, else by AceView gene names, stable from release to release. Alternative features (promoters, introns and exons, polyadenylation signals) and coding potential, including motifs, domains, and homologies are annotated in depth; tissues where expression has been observed are listed in order of representation; diseases, phenotypes, pathways, functions, localization or interactions are annotated by mining selected sources, in particular PubMed, GAD and Entrez Gene, and also by performing manual annotation, especially in the worm. In this way, both the anatomy and physiology of the experimentally cDNA supported human, mouse and nematode genes are thoroughly annotated.

Database of Interacting Proteins

DIP

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The DIP database catalogs experimentally determined interactions between proteins. It combines information from a variety of sources to create a single, consistent set of protein-protein interactions. The data stored within the DIP database were curated, both, manually by expert curators and also automatically using computational approaches that utilize the the knowledge about the protein-protein interaction networks extracted from the most reliable, core subset of the DIP data. Please, check the reference page to find articles describing the DIP database in greater detail. The Database of Ligand-Receptor Partners (DLRP) is a subset of DIP (Database of Interacting Proteins). The DLRP is a database of protein ligand and protein receptor pairs that are known to interact with each other. By interact we mean that the ligand and receptor are members of a ligand-receptor complex and, unless otherwise noted, transduce a signal. In some instances the ligand and/or receptor may form a heterocomplex with other ligands/receptors in order to be functional. We have entered the majority of interactions in DLRP as full DIP entries, with links to references and additional information

Integrated Marine Observing System Ocean Data Portal

IMOS Ocean Portal

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>>>!!!<<< duplicate >>>!!!<<< see https://www.re3data.org/repository/r3d100010914 At 2016-05-29 sees the official merger of the IMOS eMarine Information Infrastructure (eMII) Facility and the Australian Ocean Data Network (AODN) into a single entity. The marine information Facility of IMOS is now the AODN. Enabling open access to marine data is core business for IMOS. The IMOS data will continue to be discoverable alongside a wider collection of Australian marine and climate data via the new-look AODN Portal. Visit the AODN Portal at https://portal.aodn.org.au/. - All IMOS data is open access and can be discovered, accessed and downloaded via the Australian Ocean Data Network (AODN) Portal.

Upper Ocean Processes Group

UOP

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The primary focus of the Upper Ocean Processes Group is the study of physical processes in the upper ocean and at the air-sea interface using moored surface buoys equipped with meteorological and oceanographic sensors. UOP Project Map The Upper Ocean Processes Group provides technical support to upper ocean and air-sea interface science programs. Deep-ocean and shallow-water moored surface buoy arrays are designed, fabricated, instrumented, tested, and deployed at sea for periods of up to one year

Mouse Models of Human Cancer database

MMHCdb

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The Mouse Tumor Biology (MTB) Database supports the use of the mouse as a model system of hereditary cancer by providing electronic access to: Information on endogenous spontaneous and induced tumors in mice, including tumor frequency & latency data, Information on genetically defined mice (inbred, hybrid, mutant, and genetically engineered strains of mice) in which tumors arise, Information on genetic factors associated with tumor susceptibility in mice and somatic genetic-mutations observed in the tumors, Tumor pathology reports and images, References, supporting MTB data and Links to other online resources for cancer.

EUREF Permanent Network

EPN

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The EPN (or EUREF Permanent Network) is a voluntary organization of several European agencies and universities that pool resources and permanent GNSS station data to generate precise GNSS products. The EPN has been created under the umbrella of the International Association Geodesy and more precisely by its sub-commission EUREF. The European Terrestrial Reference System 89 (ETRS89) is used as the standard precise GPS coordinate system throughout Europe. Supported by EuroGeographics and endorsed by the EU, this reference system forms the backbone for all geographic and geodynamic projects on the European territory both on a national as on an international level.

WormBase

facilitating insights into nematode biology

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Launched in 2000, WormBase is an international consortium of biologists and computer scientists dedicated to providing the research community with accurate, current, accessible information concerning the genetics, genomics and biology of C. elegans and some related nematodes. In addition to their curation work, all sites have ongoing programs in bioinformatics research to develop the next generations of WormBase structure, content and accessibility

Berkeley Drosophila Genome Project

BDGP

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The goals of the Drosophila Genome Center are to finish the sequence of the euchromatic genome of Drosophila melanogaster to high quality and to generate and maintain biological annotations of this sequence. In addition to genomic sequencing, the BDGP is 1) producing gene disruptions using P element-mediated mutagenesis on a scale unprecedented in metazoans; 2) characterizing the sequence and expression of cDNAs; and 3) developing informatics tools that support the experimental process, identify features of DNA sequence, and allow us to present up-to-date information about the annotated sequence to the research community.

International Earth Rotation and Reference Systems Service

IERS

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The IERS provides data on Earth orientation, on the International Celestial Reference System/Frame, on the International Terrestrial Reference System/Frame, and on geophysical fluids. It maintains also Conventions containing models, constants and standards.

Genome Sequence Archive

GSA

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GSA is a data repository specialized for archiving raw sequence reads. It supports data generated from a variety of sequencing platforms ranging from Sanger sequencing machines to single-cell sequencing machines and provides data storing and sharing services free of charge for worldwide scientific communities. In addition to raw sequencing data, GSA also accommodates secondary analyzed files in acceptable formats (like BAM, VCF). Its user-friendly web interfaces simplify data entry and submitted data are roughly organized as two parts, viz., Metadata and File, where the former can be further assorted into BioProject, BioSample, Experiment and Run, and the latter contains raw sequence reads.

Japanese Genotype-phenotype Archive

JGA

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The Japanese Genotype-phenotype Archive (JGA) is a service for permanent archiving and sharing of all types of individual-level genetic and de-identified phenotypic data resulting from biomedical research projects. The JGA contains exclusive data collected from individuals whose consent agreements authorize data release only for specific research use or to bona fide researchers. Strict protocols govern how information is managed, stored and distributed by the JGA. Once processed, all data are encrypted. Users can contact the JGA team from here. JGA services are provided in collaboration with National Bioscience Database Center (NBDC) of Japan Science and Technology Agency.

Government of Alberta Open Datasets

Alberta Open Data

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The open government portal is a collection of datasets and publications by government departments and agencies. The public can use and access this data freely to learn more about how government works, carry out research or build web apps. The portal functions as both a library for current publications and as an archive for old publications which have historic value.

RCSB Protein Data Bank

RCSB PDB

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The Protein Data Bank (PDB) archive is the single worldwide repository of information about the 3D structures of large biological molecules, including proteins and nucleic acids. These are the molecules of life that are found in all organisms including bacteria, yeast, plants, flies, other animals, and humans. Understanding the shape of a molecule helps to understand how it works. This knowledge can be used to help deduce a structure's role in human health and disease, and in drug development. The structures in the archive range from tiny proteins and bits of DNA to complex molecular machines like the ribosome.

Centre for Environmental Data Analysis

CEDA

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The Centre for Environmental Data Analysis (CEDA) serves the environmental science community through managing data centres, data analysis environments, and participation in a host of relevant research projects. We aim to support environmental science, further environmental data archival practices, and develop and deploy new technologies to enhance access to data. Additionally we provide services to aid large scale data analysis. The CEDA Archive operates the atmospheric and earth observation data centre functions on behalf of NERC for the UK atmospheric science and earth observation communities. It covers climate, composition, observations and NWP data as well as various earth observation datasets, including airborne and satellite data and imagery. Prior to November 2016 these functions were operted by CEDA under the titles of the British Atmospheric Data Centre (BADC) and the NERC Earth Observation Data Centre (NEODC). CEDA also operates the UK Solar System Data Centre (UKSSDC), which curates and provides access to archives of data from the upper atmosphere, ionosphere and Earth's solar environment.

Strasbourg Astronomical Data Center

CDS

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Strasbourg astronomical Data Center (CDS) is dedicated to the collection and worldwide distribution of astronomical data and related information. Alongside data curation and service maintenance responsibilities, the CDS undertakes R&D activities that are fundamental to ensure the long term sustainability in a domain in which technology evolves very quickly. R&D areas include informatics, big data, and development of the astronomical Virtual Observatory (VO). CDS is a major actor in the VO with leading roles in European VO projects, the French Virtual Observatory and the International Virtual Observatory Alliance (IVOA). The CDS hosts the SIMBAD astronomical database, the world reference database for the identification of astronomical objects; VizieR, the catalogue service for the CDS reference collection of astronomical catalogues and tables published in academic journals; and the Aladin interactive software sky atlas for access, visualization and analysis of astronomical images, surveys, catalogues, databases and related data.

dbSNP

SNV

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The NCBI Short Genetic Variations database, commonly known as dbSNP, catalogs short variations in nucleotide sequences from a wide range of organisms. These variations include single nucleotide variations, short nucleotide insertions and deletions, short tandem repeats and microsatellites. Short Genetic Variations may be common, thus representing true polymorphisms, or they may be rare. Some rare human entries have additional information associated withthem, including disease associations, genotype information and allele origin, as some variations are somatic rather than germline events. ***NCBI will phase out support for non-human organism data in dbSNP and dbVar beginning on September 1, 2017***

The Microbial Protein Interaction Database

MPIDB

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>>>!!!<<< as stated 2017-06-09 MPIDB is no longer available under URL http://www.jcvi.org/mpidb/about.php >>>!!!<<< The microbial protein interaction database (MPIDB) aims to collect and provide all known physical microbial interactions. Currently, 24,295 experimentally determined interactions among proteins of 250 bacterial species/strains can be browsed and downloaded. These microbial interactions have been manually curated from the literature or imported from other databases (IntAct, DIP, BIND, MINT) and are linked to 26,578 experimental evidences (PubMed ID, PSI-MI methods). In contrast to these databases, interactions in MPIDB are further supported by 68,346 additional evidences based on interaction conservation, protein complex membership, and 3D domain contacts (iPfam, 3did). We do not include (spoke/matrix) binary interactions infered from pull-down experiments.

UniGene

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<<<!!!<<< This repository is no longer available>>>!!!>>>. Although the web pages are no longer available, you will still be able to download the final UniGene builds as static content from the FTP site https://ftp.ncbi.nlm.nih.gov/repository/UniGene/. You will also be able to match UniGene cluster numbers to Gene records by searching Gene with UniGene cluster numbers. For best results, restrict to the “UniGene Cluster Number” field rather than all fields in Gene. For example, a search with Mm.2108[UniGene Cluster Number] finds the mouse transthyretin Gene record (Ttr). You can use the advanced search page https://www.ncbi.nlm.nih.gov/gene/advanced to help construct these searches. Keep in mind that the Gene record contains selected Reference Sequences and GenBank mRNA sequences rather than the larger set of expressed sequences in the UniGene cluster.