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Found 15 result(s)
Reactome is a manually curated, peer-reviewed pathway database, annotated by expert biologists and cross-referenced to bioinformatics databases. Its aim is to share information in the visual representations of biological pathways in a computationally accessible format. Pathway annotations are authored by expert biologists, in collaboration with Reactome editorial staff and cross-referenced to many bioinformatics databases. These include NCBI Gene, Ensembl and UniProt databases, the UCSC and HapMap Genome Browsers, the KEGG Compound and ChEBI small molecule databases, PubMed, and Gene Ontology.
<<<!!!<<< This repository is no longer available. >>>!!!>>> NetPath is currently one of the largest open-source repository of human signaling pathways that is all set to become a community standard to meet the challenges in functional genomics and systems biology. Signaling networks are the key to deciphering many of the complex networks that govern the machinery inside the cell. Several signaling molecules play an important role in disease processes that are a direct result of their altered functioning and are now recognized as potential therapeutic targets. Understanding how to restore the proper functioning of these pathways that have become deregulated in disease, is needed for accelerating biomedical research. This resource is aimed at demystifying the biological pathways and highlights the key relationships and connections between them. Apart from this, pathways provide a way of reducing the dimensionality of high throughput data, by grouping thousands of genes, proteins and metabolites at functional level into just several hundreds of pathways for an experiment. Identifying the active pathways that differ between two conditions can have more explanatory power than just a simple list of differentially expressed genes and proteins.
AMCSD is an interface to a crystal structure database that includes every structure published in the American Mineralogist, The Canadian Mineralogist, European Journal of Mineralogy and Physics and Chemistry of Minerals, as well as selected datasets from other journals. The database is maintained under the care of the Mineralogical Society of America and the Mineralogical Association of Canada, and financed by the National Science Foundation. You may search by a mineral of your choice, or choose a mineral from a complete list to help aid your research.
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The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information. The latest release of DrugBank (version 5.1.1, released 2018-07-03) contains 11,881 drug entries including 2,526 approved small molecule drugs, 1,184 approved biotech (protein/peptide) drugs, 129 nutraceuticals and over 5,751 experimental drugs. Additionally, 5,132 non-redundant protein (i.e. drug target/enzyme/transporter/carrier) sequences are linked to these drug entries. Each DrugCard entry contains more than 200 data fields with half of the information being devoted to drug/chemical data and the other half devoted to drug target or protein data.
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CCCma has developed a number of climate models. These are used to study climate change and variability, and to understand the various processes which govern the climate system. They are also used to make quantitative projections of future long-term climate change (given various greenhouse gas and aerosol forcing scenarios), and increasingly to make initialized climate predictions on time scales ranging from seasons to decades. A brief description of these models and their corresponding references can be found: https://www.canada.ca/en/environment-climate-change/services/climate-change/science-research-data/modeling-projections-analysis/centre-modelling-analysis/models.html
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The CCDS is an interface for distributing climate change information. The goals of CCDS are to: Support climate change impact and adaptation research in Canada and other countries; Support stakeholders requiring scenario information for decision making and policy development. Provide access to Canadian research on the development of scenarios and adaptation research.
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Historical Climate Data (formerly: The National Climate Data and Information Archive - NCDC) is a web-based resource maintained by Environment and Climate Change Canada and the Meteorological Service of Canada. The site houses a number of statistical and data compilation and viewing tools. From the website, users can access historical climate data for Canadian locations and dates, view climate normals and averages, and climate summaries. A list of Canadian air stations and their meteorological reports and activities is also available, along with rainfall statistics for more than 500 locations across Canada. Users can also download the Canadian daily climate data for 2006/07. In addition, technical documentation is offered for data users to interpret the available data. Other documentation includes a catalogue of Canadian weather reporting stations, a glossary, and a calculation of the 1971 to 2000 climate normals for Canada. This resource carries authority and accuracy because it is maintained by a national government department and service. While the majority of the statistics are historical, the data is up-to-date and contains current and fairly recent climate data. This government resource is intended for an audience that has the ability and knowledge to interpret climatological data
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CEEHRC represents a multi-stage funding commitment by the Canadian Institutes of Health Research (CIHR) and multiple Canadian and international partners. The overall aim is to position Canada at the forefront of international efforts to translate new discoveries in the field of epigenetics into improved human health. The two sites will focus on sequencing human reference epigenomes and developing new technologies and protocols; they will also serve as platforms for other CEEHRC funding initiatives, such as catalyst and team grants. The complementary reference epigenome mapping efforts of the two sites will focus on a range of common human diseases. The Vancouver group will focus on the role of epigenetics in the development of cancer, including lymphoma and cancers of the ovary, colon, breast, and thyroid. The Montreal team will focus on autoimmune / inflammatory, cardio-metabolic, and neuropsychiatric diseases, using studies of identical twins as well as animal models of human disease.
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>>>>!!!<<< NEPTUNE Canada is now part of Ocean Networks Canada and this website is being phased out. Please visit us on our new website at oceannetworks.ca >>>!!!<<< NEPTUNE Canada, the North-East Pacific Time-series Undersea Networked Experiments, is the world's first regional scale cabled deep ocean observing network. It consists of an 800km network of electro‐optic cable laid on the seabed over the northern Juan de Fuca tectonic plate, off the coast of British Columbia. This tectonic plate serves as an exceptional natural laboratory for ocean observation and experiments. NEPTUNE Canada instruments yield continuous real‐time data and imagery from the ocean surface to beneath the seafloor, and from the coast to the deep sea. They respond to events such as earthquakes, tsunamis, fish migrations, plankton blooms, storms and volcanic eruptions. NEPTUNE Canada offers a unique and exciting approach to ocean science.
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The Queen's Research Data Centre is a member of the Canadian Research Data Centre Network (CRDCN) that provides researchers with access to microdata 'masterfiles' from population and health surveys. Access to the RDC is limited to those with projects approved by Statistics Canada. Before applying to an RDC, you will have to show that your research cannot be conducted using Public Use Microdata Files (PUMFs) available through the Data Liberation Initiative (DLI). Access to DLI PUMFS at Queen's is available through the Social Science Data Centre, using the ODESI data portal.
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The Large Fire Database (LFDB) is a compilation of forest fire data from all Canadian agencies, including provinces, territories, and Parks Canada. The data set includes only fires greater than 200 hectares in final size; these represent only a few percent of all fires but account for most of the area burned (usually more than 97%). Therefore, the LFDB can be used for spatial and temporal analyses of landscape-scale fire impacts. For information on smaller fires (up to 200 ha in final size), please contact individual fire agencies. Links to other agencies can be found through the Canadian Interagency Forest Fire Centre (CIFFC).
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HYDAT is the archival database that contains all water information collected through the National Hydrometric Program. These data include: daily and monthly mean flow, water level and sediment concentration for over 2500 active and 5500 discontinued hydrometric monitoring station across Canada. HYDEX is a relational database that contains inventory information on the various streamflow, water level, and sediment stations (both active and discontinued) in Canada. This database contains information about the stations themselves, such as location, equipment, and type(s) of data collected.
KADoNiS-p database: The KADoNiS project is an online database for cross sections relevant to the s-process and p-process (γ-process). The present p-process library includes all available experimental data from (p,γ), (p,n), (α,γ), (α,n), and (α,p) reactions between 70Ge and 209Bi in or close to the respective Gamow window.