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Found 8 result(s)
The IMPC is a confederation of international mouse phenotyping projects working towards the agreed goals of the consortium: To undertake the phenotyping of 20,000 mouse mutants over a ten year period, providing the first functional annotation of a mammalian genome. Maintain and expand a world-wide consortium of institutions with capacity and expertise to produce germ line transmission of targeted knockout mutations in embryonic stem cells for 20,000 known and predicted mouse genes. Test each mutant mouse line through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease. Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems; Maintain and expand collaborative “networks” with specialist phenotyping consortia or laboratories, providing standardized secondary level phenotyping that enriches the primary dataset, and end-user, project specific tertiary level phenotyping that adds value to the mammalian gene functional annotation and fosters hypothesis driven research; and Provide a centralized data centre and portal for free, unrestricted access to primary and secondary data by the scientific community, promoting sharing of data, genotype-phenotype annotation, standard operating protocols, and the development of open source data analysis tools. Members of the IMPC may include research centers, funding organizations and corporations.
Country
Rodare is the institutional research data repository at HZDR (Helmholtz-Zentrum Dresden-Rossendorf). Rodare allows HZDR researchers to upload their research software and data and enrich those with metadata to make them findable, accessible, interoperable and retrievable (FAIR). By publishing all associated research software and data via Rodare research reproducibility can be improved. Uploads receive a Digital Object Identfier (DOI) and can be harvested via a OAI-PMH interface.
The German Text Archive (Deutsches Textarchiv, DTA) presents online a selection of key German-language works in various disciplines from the 17th to 19th centuries. The electronic full-texts are indexed linguistically and the search facilities tolerate a range of spelling variants. The DTA presents German-language printed works from around 1650 to 1900 as full text and as digital facsimile. The selection of texts was made on the basis of lexicographical criteria and includes scientific or scholarly texts, texts from everyday life, and literary works. The digitalisation was made from the first edition of each work. Using the digital images of these editions, the text was first typed up manually twice (‘double keying’). To represent the structure of the text, the electronic full-text was encoded in conformity with the XML standard TEI P5. The next stages complete the linguistic analysis, i.e. the text is tokenised, lemmatised, and the parts of speech are annotated. The DTA thus presents a linguistically analysed, historical full-text corpus, available for a range of questions in corpus linguistics. Thanks to the interdisciplinary nature of the DTA Corpus, it also offers valuable source-texts for neighbouring disciplines in the humanities, and for scientists, legal scholars and economists.
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GESIS preserves (mainly quantitative) social research data to make it available to the scientific research community. The data is described in a standardized way, secured for the long term, provided with a permanent identifier (DOI), and can be easily found and reused through browser-optimized catalogs (https://search.gesis.org/).
DEPOD - the human DEPhOsphorylation Database (version 1.1) is a manually curated database collecting human active phosphatases, their experimentally verified protein and non-protein substrates and dephosphorylation site information, and pathways in which they are involved. It also provides links to popular kinase databases and protein-protein interaction databases for these phosphatases and substrates. DEPOD aims to be a valuable resource for studying human phosphatases and their substrate specificities and molecular mechanisms; phosphatase-targeted drug discovery and development; connecting phosphatases with kinases through their common substrates; completing the human phosphorylation/dephosphorylation network.
Country
The ZBW Digital Long-Term Archive is a dark archive whose sole purpose is to guarantee the long term availability of the objects stored in it. The storage for the ZBW’s digital objects and their representation platforms is maintained by the ZBW division IT-Infrastructures and is not part of the tasks of the group Digital Preservation. The content that the ZBW provides is accessible via special representation platforms. The special representation platforms are: EconStor: an open access publication server for literature on business and economics. ZBW DIGITAL ARCHIVE: it contains born digital material from the domains of business and economics. The content of this archive is accessible in open access via EconBiz, the subject portal for business and economics of the ZBW. National and Alliance Licenses: the ZBW negotiates and curates licenses for electronic products on a national level. This is processed under the framework of the German Research Foundation as well as the Alliance of Science Associations, partly with third party funding, partly solely funded by the ZBW. A part of these electronic products is already hosted by the ZBW and counts among the items that are preserved in the digital archive. 20th Century Press Archive: a portal with access to archival material consisting of press clippings from newspapers covering the time period from the beginning of the 20th century to the year 1949.
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DBT is the institutional repository of the FSU Jena, the TU Ilmenau and the University of Erfurt as well as members of the other Thuringian universities and colleges can publish scientific documents in the DBT. In individual cases, land users (via the ThULB Jena) can also archive documents in the DBT.