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The IMPC is a confederation of international mouse phenotyping projects working towards the agreed goals of the consortium: To undertake the phenotyping of 20,000 mouse mutants over a ten year period, providing the first functional annotation of a mammalian genome. Maintain and expand a world-wide consortium of institutions with capacity and expertise to produce germ line transmission of targeted knockout mutations in embryonic stem cells for 20,000 known and predicted mouse genes. Test each mutant mouse line through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease. Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems; Maintain and expand collaborative “networks” with specialist phenotyping consortia or laboratories, providing standardized secondary level phenotyping that enriches the primary dataset, and end-user, project specific tertiary level phenotyping that adds value to the mammalian gene functional annotation and fosters hypothesis driven research; and Provide a centralized data centre and portal for free, unrestricted access to primary and secondary data by the scientific community, promoting sharing of data, genotype-phenotype annotation, standard operating protocols, and the development of open source data analysis tools. Members of the IMPC may include research centers, funding organizations and corporations.
The long-term goal of this project is to implement a new strategy for preserving and providing access to the Astrophysical data heritage. IA2 is an ambitious Italian Astrophysical research infrastructure project that aims at co-ordinating different national initiatives to improve the quality of astrophysical data services. It aims at co-ordinating these developments and facilitating access to this data for research purposes. The first working target, is the implementation of the TNG Long-Term Archive (LTA). Its feasibility was demonstrated by the LTA pilot project prototype, funded by CNAA in 2001 and completed successfully in July 2002. The implementation of the TNG archive implies: − interfacing with the Centro "Galileo Galilei" (CGG) for the acquisition of TNG data; − long-term storage of scientific, technical and auxiliary data from the TNG; − providing accessibility by the CGG staff and by the scientific community to original and derived data; − providing tools to support the life cycle of observing proposals. The second target of the proposal aims at ensuring harmonization with other projects related to archiving of data of astrophysical interest, with particular reference to projects involving the Italian astronomical community (LBT, VST, GSC-II, DPOSS, …), to the Italian Solar and Solar System Physics community (SOLAR, SOLRA, ARTHEMIS which form SOLARNET – a future node of EGSO) and to the national and international coordination efforts fostering the idea of a multiwavelength Virtual Astronomical Observatory, and the use of the archived data through the Italian Astronomical Grid.
virus mentha archives evidence about viral interactions collected from different sources and presents these data in a complete and comprehensive way. Its data comes from manually curated protein-protein interaction databases that have adhered to the IMEx consortium. virus mentha is a resource that offers a series of tools to analyse selected proteins in the context of a network of interactions. Protein interaction databases archive protein-protein interaction (PPI) information from published articles. However, no database alone has sufficient literature coverage to offer a complete resource to investigate "the interactome". virus mentha's approach generates every week a consistent interactome (graph). Most importantly, the procedure assigns to each interaction a reliability score that takes into account all the supporting evidence. virus mentha offers direct access to viral families such as: Orthomyxoviridae, Orthoretrovirinae and Herpesviridae plus, it offers the unique possibility of searching by host organism. The website and the graphical application are designed to make the data stored in virus mentha accessible and analysable to all users.virus mentha superseeds VirusMINT. The Source databases are: MINT, DIP, IntAct, MatrixDB, BioGRID.
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Research Data Unipd is a data archive and supports research produced by the members of the University of Padova. The service aims to facilitate data discovery, data sharing, and reuse, as required by funding institutions (eg. European Commission). Datasets published in the archive have a set of metadata that ensure proper description and discoverability.