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Found 66 result(s)
STRING is a database of known and predicted protein interactions. The interactions include direct (physical) and indirect (functional) associations; they are derived from four sources: - Genomic Context - High-throughput Experiments - (Conserved) Coexpression - Previous Knowledge STRING quantitatively integrates interaction data from these sources for a large number of organisms, and transfers information between these organisms where applicable.
WFCC Global Catalogue of Microorganisms (GCM) is expected to be a robust, reliable and user-friendly system to help culture collections to manage, disseminate and share the information related to their holdings. It also provides a uniform interface for the scientific and industrial communities to access the comprehensive microbial resource information.
The Comprehensive Epidemiologic Data Resource (CEDR) is the Department of Energy's (DOE) electronic database comprised of health studies of DOE contract workers and environmental studies of areas surrounding DOE facilities. DOE recognizes the benefits of data sharing and supports the public's right to know about worker and community health risks. CEDR provides independent researchers and the public with access to de-identified data collected since the Department's early production years. Current CEDR holdings include more than 80 studies of over 1 million workers at 31 DOE sites. Access to these data is at no cost to the user. Most of CEDR's holdings are derived from epidemiologic studies of DOE workers at many large nuclear weapons plants, such as Hanford, Los Alamos, the Oak Ridge reservation, Savannah River Site, and Rocky Flats. These studies primarily use death certificate information to identify excess deaths and patterns of disease among workers to determine what factors contribute to the risk of developing cancer and other illnesses. In addition, many of these studies have radiation exposure measurements on individual workers. CEDR is supported by the Oak Ridge Institute for Science and Education (ORISE) in Oak Ridge, Tennessee. Now a mature system in routine operational use, CEDR's modern internet-based systems respond to thousands of requests to its web server daily. With about 1,500 Internet sites pointing to CEDR's web site, CEDR is a national user facility, with a large audience for data that are not available elsewhere.
SeaBASS, the publicly shared archive of in situ oceanographic and atmospheric data maintained by the NASA Ocean Biology Processing Group (OBPG). High quality in situ measurements are prerequisite for satellite data product validation, algorithm development, and many climate-related inquiries. As such, the NASA Ocean Biology Processing Group (OBPG) maintains a local repository of in situ oceanographic and atmospheric data to support their regular scientific analyses. The SeaWiFS Project originally developed this system, SeaBASS, to catalog radiometric and phytoplankton pigment data used their calibration and validation activities. To facilitate the assembly of a global data set, SeaBASS was expanded with oceanographic and atmospheric data collected by participants in the SIMBIOS Program, under NASA Research Announcements NRA-96 and NRA-99, which has aided considerably in minimizing spatial bias and maximizing data acquisition rates. Archived data include measurements of apparent and inherent optical properties, phytoplankton pigment concentrations, and other related oceanographic and atmospheric data, such as water temperature, salinity, stimulated fluorescence, and aerosol optical thickness. Data are collected using a number of different instrument packages, such as profilers, buoys, and hand-held instruments, and manufacturers on a variety of platforms, including ships and moorings.
The VDC is a public, web-based search engine for accessing worldwide earthquake strong ground motion data. While the primary focus of the VDC is on data of engineering interest, it is also an interactive resource for scientific research and government and emergency response professionals.
TES is the first satellite instrument to provide simultaneous concentrations of carbon monoxide, ozone, water vapor and methane throughout Earth’s lower atmosphere. This lower atmosphere (the troposphere) is situated between the surface and the height at which aircraft fly, and is an important part of the atmosphere that we often impact with our activities.
AmoebaDB belongs to the EuPathDB family of databases and is an integrated genomic and functional genomic database for Entamoeba and Acanthamoeba parasites. In its first iteration (released in early 2010), AmoebaDB contains the genomes of three Entamoeba species (see below). AmoebaDB integrates whole genome sequence and annotation and will rapidly expand to include experimental data and environmental isolate sequences provided by community researchers . The database includes supplemental bioinformatics analyses and a web interface for data-mining.
OrthoMCL is a genome-scale algorithm for grouping orthologous protein sequences. It provides not only groups shared by two or more species/genomes, but also groups representing species-specific gene expansion families. So it serves as an important utility for automated eukaryotic genome annotation. OrthoMCL starts with reciprocal best hits within each genome as potential in-paralog/recent paralog pairs and reciprocal best hits across any two genomes as potential ortholog pairs. Related proteins are interlinked in a similarity graph. Then MCL (Markov Clustering algorithm,Van Dongen 2000; www.micans.org/mcl) is invoked to split mega-clusters. This process is analogous to the manual review in COG construction. MCL clustering is based on weights between each pair of proteins, so to correct for differences in evolutionary distance the weights are normalized before running MCL.
VAMDC aims to be an interoperable e-infrastructure that provides the international research community with access to a broad range of atomic and molecular (A&M) data compiled within a set of A&M databases accessible through the provision of this portal and of user software. Furthermore VAMDC aims to provide A&M data providers and compilers with a large dissemination platform for their work. VAMDC infrastructure was established to provide a service to a wide international research community and has been developed in conjunction with consultations and advice from the A&M user community.
The Deep Blue Data repository is a means for University of Michigan researchers to make their research data openly accessible to anyone in the world, provided they meet collections criteria. Submitted data sets undergo a curation review by librarians to support discovery, understanding, and reuse of the data.
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Research Data Australia is the data discovery service of the Australian National Data Service (ANDS). We do not store the data itself here but provide descriptions of, and links to, the data from our data publishing partners. ANDS is funded by the Australian Government through the National Collaborative Research Infrastructure Strategy (NCRIS).
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The Norwegian Marine Data Centre (NMD) at the Institute of Marine Research was established as a national data centre dedicated to the professional processing and long-term storage of marine environmental and fisheries data and production of data products. The Institute of Marine Research continuously collects large amounts of data from all Norwegian seas. Data are collected using vessels, observation buoys, manual measurements, gliders – amongst others. NMD maintains the largest collection of marine environmental and fisheries data in Norway.
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The information system Graffiti in Germany (INGRID) is a cooperation project between the linguistics department at the University of Paderborn and the art history department at the Karlsruhe Institute of Technology (KIT). As part of the joint project, graffiti image collections will be compiled, stored in an image database and made available for scientific use. At present, more than 100,000 graffiti from the years 1983 to 2018 from major German cities are recorded, including Cologne, Mannheim and Munich.
The ADS is an accredited digital repository for heritage data that supports research, learning and teaching with freely available, high quality and dependable digital resources by preserving and disseminating digital data in the long term. The ADS also promotes good practice in the use of digital data, provides technical advice to the heritage community, and supports the deployment of digital technologies.
The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc). The UniProt Metagenomic and Environmental Sequences (UniMES) database is a repository specifically developed for metagenomic and environmental data.
The PeptideAtlas validates expressed proteins to provide eukaryotic genome data. Peptide Atlas provides data to advance biological discoveries in humans. The PeptideAtlas accepts proteomic data from high-throughput processes and encourages data submission.
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The Australian National Corpus collates and provides access to assorted examples of Australian English text, transcriptions, audio and audio-visual materials. Text analysis tools are embedded in the interface allowing analysis and downloads in *.CSV format.
Giardia lamblia is a significant, environmentally transmitted, human pathogen and an amitochondriate protist. It is a major contributor to the enormous worldwide burden of human diarrheal diseases, yet the basic biology of this parasite is not well understood. No virulence factor has been identified. The Giardia lamblia genome contains only 12 million base pairs distributed onto five chromosomes. Its analysis promises to provide insights about the origins of nuclear genome organization, the metabolic pathways used by parasitic protists, and the cellular biology of host interaction and avoidance of host immune systems. Since the divergence of Giardia lamblia lies close to the transition between eukaryotes and prokaryotes in universal ribosomal RNA phylogenies, it is a valuable, if not unique, model for gaining basic insights into genetic innovations that led to formation of eukaryotic cells. In evolutionary terms, the divergence of this organism is at least twice as ancient as the common ancestor for yeast and man. A detailed study of its genome will provide insights into an early evolutionary stage of eukaryotic chromosome organization as well as other aspects of the prokaryotic / eukaryotic divergence.
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The Life Science Database Archive maintains and stores the datasets generated by life scientists in Japan in a long-term and stable state as national public goods. The Archive makes it easier for many people to search datasets by metadata (description of datasets) in a unified format, and to access and download the datasets with clear terms of use. In addition, the Archive provides datasets in forms friendly to different types of users in public and private institutions, and thereby supports further contribution of each research to life science.
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MTD is focused on mammalian transcriptomes with a current version that contains data from humans, mice, rats and pigs. Regarding the core features, the MTD browses genes based on their neighboring genomic coordinates or joint KEGG pathway and provides expression information on exons, transcripts, and genes by integrating them into a genome browser. We developed a novel nomenclature for each transcript that considers its genomic position and transcriptional features.
The International Center for Global Earth Models collects and distributes historical and actual global gravity field models of the Earth and offers calculation service for derived quantities. In particular the tasks include: collecting and archiving of all existing global gravity field models, web interface for getting access to global gravity field models, web based visualization of the gravity field models their differences and their time variation, web based service for calculating different functionals of the gravity field models, web site for tutorials on spherical harmonics and the theory of the calculation service. As new service since 2016, ICGEM is providing a Digital Object Identifier (DOI) for the data set of the model (the coefficients).
The CLARIN Centre at the University of Copenhagen, Denmark, hosts and manages a data repository (CLARIN-DK-UCPH Repository), which is part of a research infrastructure for humanities and social sciences financed by the University of Copenhagen, and a part of the national infrastructure collaboration DIGHUMLAB in Denmark. The CLARIN-DK-UCPH Repository provides easy and sustainable access for scholars in the humanities and social sciences to digital language data (in written, spoken, video or multimodal form) and provides advanced tools for discovering, exploring, exploiting, annotating, and analyzing data. CLARIN-DK also shares knowledge on Danish language technology and resources and is the Danish node in the European Research Infrastructure Consortium, CLARIN ERIC.
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TopFIND is a protein-centric database for the annotation of protein termini currently in its third version. Non-canonical protein termini can be the result of multiple different biological processes, including pre-translational processes such as alternative splicing and alternative translation initiation or post-translational protein processing by proteases that cleave proteases as part of protein maturation or as a regulatory modification. Accordingly, protein termini evidence in TopFIND is inferred from other databases such as ENSEMBL transcripts, TISdb for alternative translation initiation, MEROPS for protein cleavage by proteases, and UniProt for canonical and protein isoform start sites.
The R2R Portal is a central shore-side gateway through which underway data from oceanographic expeditions will be routinely cataloged and securely transmitted to the national long-term archives including the National Geophysical Data Center (NGDC) and National Oceanographic Data Center (NODC).