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Found 34 result(s)
STRING is a database of known and predicted protein interactions. The interactions include direct (physical) and indirect (functional) associations; they are derived from four sources: - Genomic Context - High-throughput Experiments - (Conserved) Coexpression - Previous Knowledge STRING quantitatively integrates interaction data from these sources for a large number of organisms, and transfers information between these organisms where applicable.
The Comprehensive Epidemiologic Data Resource (CEDR) is the Department of Energy's (DOE) electronic database comprised of health studies of DOE contract workers and environmental studies of areas surrounding DOE facilities. DOE recognizes the benefits of data sharing and supports the public's right to know about worker and community health risks. CEDR provides independent researchers and the public with access to de-identified data collected since the Department's early production years. Current CEDR holdings include more than 80 studies of over 1 million workers at 31 DOE sites. Access to these data is at no cost to the user. Most of CEDR's holdings are derived from epidemiologic studies of DOE workers at many large nuclear weapons plants, such as Hanford, Los Alamos, the Oak Ridge reservation, Savannah River Site, and Rocky Flats. These studies primarily use death certificate information to identify excess deaths and patterns of disease among workers to determine what factors contribute to the risk of developing cancer and other illnesses. In addition, many of these studies have radiation exposure measurements on individual workers. CEDR is supported by the Oak Ridge Institute for Science and Education (ORISE) in Oak Ridge, Tennessee. Now a mature system in routine operational use, CEDR's modern internet-based systems respond to thousands of requests to its web server daily. With about 1,500 Internet sites pointing to CEDR's web site, CEDR is a national user facility, with a large audience for data that are not available elsewhere.
The VDC is a public, web-based search engine for accessing worldwide earthquake strong ground motion data. While the primary focus of the VDC is on data of engineering interest, it is also an interactive resource for scientific research and government and emergency response professionals.
TES is the first satellite instrument to provide simultaneous concentrations of carbon monoxide, ozone, water vapor and methane throughout Earth’s lower atmosphere. This lower atmosphere (the troposphere) is situated between the surface and the height at which aircraft fly, and is an important part of the atmosphere that we often impact with our activities.
OrthoMCL is a genome-scale algorithm for grouping orthologous protein sequences. It provides not only groups shared by two or more species/genomes, but also groups representing species-specific gene expansion families. So it serves as an important utility for automated eukaryotic genome annotation. OrthoMCL starts with reciprocal best hits within each genome as potential in-paralog/recent paralog pairs and reciprocal best hits across any two genomes as potential ortholog pairs. Related proteins are interlinked in a similarity graph. Then MCL (Markov Clustering algorithm,Van Dongen 2000; www.micans.org/mcl) is invoked to split mega-clusters. This process is analogous to the manual review in COG construction. MCL clustering is based on weights between each pair of proteins, so to correct for differences in evolutionary distance the weights are normalized before running MCL.
The Deep Blue Data repository is a means for University of Michigan researchers to make their research data openly accessible to anyone in the world, provided they meet collections criteria. Submitted data sets undergo a curation review by librarians to support discovery, understanding, and reuse of the data.
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Research Data Australia is the data discovery service of the Australian National Data Service (ANDS). We do not store the data itself here but provide descriptions of, and links to, the data from our data publishing partners. ANDS is funded by the Australian Government through the National Collaborative Research Infrastructure Strategy (NCRIS).
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The Norwegian Marine Data Centre (NMD) at the Institute of Marine Research was established as a national data centre dedicated to the professional processing and long-term storage of marine environmental and fisheries data and production of data products. The Institute of Marine Research continuously collects large amounts of data from all Norwegian seas. Data are collected using vessels, observation buoys, manual measurements, gliders – amongst others. NMD maintains the largest collection of marine environmental and fisheries data in Norway.
The ADS is an accredited digital repository for heritage data that supports research, learning and teaching with freely available, high quality and dependable digital resources by preserving and disseminating digital data in the long term. The ADS also promotes good practice in the use of digital data, provides technical advice to the heritage community, and supports the deployment of digital technologies.
The PeptideAtlas validates expressed proteins to provide eukaryotic genome data. Peptide Atlas provides data to advance biological discoveries in humans. The PeptideAtlas accepts proteomic data from high-throughput processes and encourages data submission.
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The Australian National Corpus collates and provides access to assorted examples of Australian English text, transcriptions, audio and audio-visual materials. Text analysis tools are embedded in the interface allowing analysis and downloads in *.CSV format.
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The Life Science Database Archive maintains and stores the datasets generated by life scientists in Japan in a long-term and stable state as national public goods. The Archive makes it easier for many people to search datasets by metadata (description of datasets) in a unified format, and to access and download the datasets with clear terms of use. In addition, the Archive provides datasets in forms friendly to different types of users in public and private institutions, and thereby supports further contribution of each research to life science.
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MTD is focused on mammalian transcriptomes with a current version that contains data from humans, mice, rats and pigs. Regarding the core features, the MTD browses genes based on their neighboring genomic coordinates or joint KEGG pathway and provides expression information on exons, transcripts, and genes by integrating them into a genome browser. We developed a novel nomenclature for each transcript that considers its genomic position and transcriptional features.
The International Center for Global Earth Models collects and distributes historical and actual global gravity field models of the Earth and offers calculation service for derived quantities. In particular the tasks include: collecting and archiving of all existing global gravity field models, web interface for getting access to global gravity field models, web based visualization of the gravity field models their differences and their time variation, web based service for calculating different functionals of the gravity field models, web site for tutorials on spherical harmonics and the theory of the calculation service. As new service since 2016, ICGEM is providing a Digital Object Identifier (DOI) for the data set of the model (the coefficients).
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TopFIND is a protein-centric database for the annotation of protein termini currently in its third version. Non-canonical protein termini can be the result of multiple different biological processes, including pre-translational processes such as alternative splicing and alternative translation initiation or post-translational protein processing by proteases that cleave proteases as part of protein maturation or as a regulatory modification. Accordingly, protein termini evidence in TopFIND is inferred from other databases such as ENSEMBL transcripts, TISdb for alternative translation initiation, MEROPS for protein cleavage by proteases, and UniProt for canonical and protein isoform start sites.
The R2R Portal is a central shore-side gateway through which underway data from oceanographic expeditions will be routinely cataloged and securely transmitted to the national long-term archives including the National Geophysical Data Center (NGDC) and National Oceanographic Data Center (NODC).
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DataStream is an open access platform for sharing information on freshwater health. It currently allows users to access, visualize, and download full water quality datasets collected by Indigenous Nations, community groups, researchers and governments throughout three regional hubs in the Mackenzie River Basin, Lake Winnipeg watershed, and across Atlantic Canada.
CryptoDB is an integrated genomic and functional genomic database for the parasite Cryptosporidium and other related genera. CryptoDB integrates whole genome sequence and annotation along with experimental data and environmental isolate sequences provided by community researchers. The database includes supplemental bioinformatics analyses and a web interface for data-mining.
The Immunology Database and Analysis Portal (ImmPort) archives clinical study and trial data generated by NIAID/DAIT-funded investigators. Data types housed in ImmPort include subject assessments i.e., medical history, concomitant medications and adverse events as well as mechanistic assay data such as flow cytometry, ELISA, ELISPOT, etc. --- You won't need an ImmPort account to search for compelling studies, peruse study demographics, interventions and mechanistic assays. But why stop there? What you really want to do is download the study, look at each experiment in detail including individual ELISA results and flow cytometry files. Perhaps you want to take those flow cytometry files for a test drive using FLOCK in the ImmPort flow cytometry module. To download all that interesting data you will need to register for ImmPort access.
MicrosporidiaDB belongs to the EuPathDB family of databases and is an integrated genomic and functional genomic database for the phylum Microsporidia. In its first iteration (released in early 2010), MicrosporidiaDB contains the genomes of two Encephalitozoon species (see below). MicrosporidiaDB integrates whole genome sequence and annotation and will rapidly expand to include experimental data and environmental isolate sequences provided by community researchers. The database includes supplemental bioinformatics analyses and a web interface for data-mining.
Earthdata powered by EOSDIS (Earth Observing System Data and Information System) is a key core capability in NASA’s Earth Science Data Systems Program. It provides end-to-end capabilities for managing NASA’s Earth science data from various sources – satellites, aircraft, field measurements, and various other programs. EOSDIS uses the metadata and service discovery tool Earthdata Search https://search.earthdata.nasa.gov/. The capabilities of EOSDIS constituting the EOSDIS Science Operations are managed by NASA's Earth Science Data and Information System (ESDIS) Project. The capabilities include: generation of higher level (Level 1-4) science data products for several satellite missions; archiving and distribution of data products from Earth observation satellite missions, as well as aircraft and field measurement campaigns. The EOSDIS science operations are performed within a distributed system of many interconnected nodes - Science Investigator-led Processing Systems (SIPS), and distributed, discipline-specific, Earth science Distributed Active Archive Centers (DAACs) with specific responsibilities for production, archiving, and distribution of Earth science data products. The DAACs serve a large and diverse user community by providing capabilities to search and access science data products and specialized services.