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Found 85 result(s)
BioModels is a repository of mathematical models of biological and biomedical systems. It hosts a vast selection of existing literature-based physiologically and pharmaceutically relevant mechanistic models in standard formats. Our mission is to provide the systems modelling community with reproducible, high-quality, freely-accessible models published in the scientific literature.
The dbVar is a database of genomic structural variation containing data from multiple gene studies. Users can browse data containing the number of variant cells from each study, and filter studies by organism, study type, method and genomic variant. Organisms include human, mouse, cattle and several additional animals. ***NCBI will phase out support for non-human organism data in dbSNP and dbVar beginning on September 1, 2017 ***
Satellite-tracked drifting buoys ("drifters") collect measurements of upper ocean currents and sea surface temperatures (SST) around the world as part of the Global Drifter Program. Drifter locations are estimated from 16-20 satellite fixes per day, per drifter. The Drifter Data Assembly Center (DAC) at NOAA's Atlantic Oceanographic and Meteorological Laboratory (AOML) assembles these raw data, applies quality control procedures, and interpolates them via kriging to regular six-hour intervals. The raw observations and processed data are archived at AOML and at the Marine Environmental Data Services (MEDS) in Canada. Two types of data are available: "metadata" contains deployment location and time, time of drogue (sea anchor) loss, date of final transmission, etc. for each drifter. "Interpolated data" contains the quality-controlled, interpolated drifter observations.
Cryo electron microscopy enables the determination of 3D structures of macromolecular complexes and cells from 2 to 100 Å resolution. EMDataResource is the unified global portal for one-stop deposition and retrieval of 3DEM density maps, atomic models and associated metadata, and is a joint effort among investigators of the Stanford/SLAC CryoEM Facility and the Research Collaboratory for Structural Bioinformatics (RCSB) at Rutgers, in collaboration with the EMDB team at the European Bioinformatics Institute. EMDataResource also serves as a resource for news, events, software tools, data standards, and validation methods for the 3DEM community. The major goal of the EMDataResource project in the current funding period is to work with the 3DEM community to (1) establish data-validation methods that can be used in the process of structure determination, (2) define the key indicators of a well-determined structure that should accompany every deposition, and (3) implement appropriate validation procedures for maps and map-derived models into a 3DEM validation pipeline.
The Sequence Read Archive stores the raw sequencing data from such sequencing platforms as the Roche 454 GS System, the Illumina Genome Analyzer, the Applied Biosystems SOLiD System, the Helicos Heliscope, and the Complete Genomics. It archives the sequencing data associated with RNA-Seq, ChIP-Seq, Genomic and Transcriptomic assemblies, and 16S ribosomal RNA data.
<<<!!!<<< The NCBI BioSystems Database will be retired in March 2022. >>>!!!>>> This retirement includes the representation of BioSystems records in the NCBI Entrez system and viewers of BioSystems content. NCBI now provides metabolic pathway and other biosystems data through the regularly updated PubChem Pathways resource (https://pubchemdocs.ncbi.nlm.nih.gov/pathways) that offers a fresh, extended, and more modern interface.
The WDC has a FTP-server to distribute the PCN index derived from the geomagnetic observatory Qaanaaq (THL) and the Kp-index data products derived at the geomagnetic observatory Niemegk (NGK). The WDC is also holding extensive archives of magnetograms and other geomagnetic observatory data products that predate the introduction of digital data recording. The material is in analogue form such as film or microfiche. The Polar Cap index (abbreviation PC index) consists of the Polar Cap North (PCN) and the Polar Cap South (PCS) index, which are derived from magnetic measurements taken at the geomagnetic observatories Qaanaaq (THL, Greenland, +85o magnetic latitude) and Vostok (VOS, Antarctica, -83o magnetic latitude), respectively. The idea behind these indices is to estimate the intensity of anti-sunward plasma convection in the polar caps. This convection is associated with electric Hall currents and consequent magnetic field variations perpendicular to the antisunward plasma flow (and related Hall current) which can be monitored at the Qaanaaq and Vostok magnetic observatories. PC aims at monitoring the energy input from solar wind to the magnetosphere (loading activity). The index is constructed in such a way that it has a linear relationship with the merging Electric Field at the magnetopause; consequently PC is given in units of mV/m as for the electric field. In August 2013, the International Association of Geomagnetism and Aeronomy (IAGA) endorsed the PC index. The endorsed PC index is accessible at pcindex.org or through WDC Copenhagen.
PDBe is the European resource for the collection, organisation and dissemination of data on biological macromolecular structures. In collaboration with the other worldwide Protein Data Bank (wwPDB) partners - the Research Collaboratory for Structural Bioinformatics (RCSB) and BioMagResBank (BMRB) in the USA and the Protein Data Bank of Japan (PDBj) - we work to collate, maintain and provide access to the global repository of macromolecular structure data. We develop tools, services and resources to make structure-related data more accessible to the biomedical community.
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The Astronomical Data Archives Center (ADAC) provides access to astronomical data from all over the world with links to online data catalogs, journal archives, imaging services and data archives. Users can access the VizieR catalogue service as well as the Hubble Ultra Deep Field Data by requesting password access. ADAC also provides access to the SMOKA public science data obtained through the Subaru Telescope in Hawaii as well as Schmidt Telescope at the University of Tokyo & MITSuME and KANATA Telescope at Higashi-Hiroshima Observatory. Users may need to contact the ADAC for password access or create user accounts for the various data services accessible through the ADAC site.
The RESID Database of Protein Modifications is a comprehensive collection of annotations and structures for protein modifications including amino-terminal, carboxyl-terminal and peptide chain cross-link post-translational modifications.
NSIDC offers hundreds of scientific data sets for research, focusing on the cryosphere and its interactions. Data are from satellites and field observations. All data are free of charge.
Rhea is a freely available and comprehensive resource of expert-curated biochemical reactions. It has been designed to provide a non-redundant set of chemical transformations for applications such as the functional annotation of enzymes, pathway inference and metabolic network reconstruction. There are three types of reaction participants (reactants and products): Small molecules, Rhea polymers, Generic compounds. All three types of reaction participants are linked to the ChEBI database (Chemical Entities of Biological Interest) which provides detailed information about structure, formula and charge. Rhea provides built-in validations that ensure both mass and charge balance of the reactions. We have populated the database with the reactions found in the enzyme classification (i.e. in the IntEnz and ENZYME databases), extending it with additional known reactions of biological interest. While the main focus of Rhea is enzyme-catalysed reactions, other biochemical reactions (including those that are often termed "spontaneous") also are included.
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The CliSAP-Integrated Climate Data Center (ICDC) allows easy access to climate relevant data from satellite remote sensing and in situ and other measurements in Earth System Sciences. These data are important to determine the status and the changes in the climate system. Additionally some relevant re-analysis data are included, which are modeled on the basis of observational data. ICDC cooperates with the "Zentrum für Nachhaltiges Forschungsdatenmanagement "https://www.fdr.uni-hamburg.de/ to publish observational data with a doi.
Polish CLARIN node – CLARIN-PL Language Technology Centre – is being built at Wrocław University of Technology. The LTC is addressed to scholars in the humanities and social sciences. Registered users are granted free access to digital language resources and advanced tools to explore them. They can also archive and share their own language data (in written, spoken, video or multimodal form).
MERMex is focused on the biogeochemical changes that will take place in the Mediterranean Sea due to natural changes as well as the socio-economic impacts, and how they will affect marine ecosystems and biodiversity.
IRIS offers free and open access to a comprehensive data store of raw geophysical time-series data collected from a large variety of sensors, courtesy of a vast array of US and International scientific networks, including seismometers (permanent and temporary), tilt and strain meters, infrasound, temperature, atmospheric pressure and gravimeters, to support basic research aimed at imaging the Earth's interior.
The Complex Portal is a manually curated, encyclopaedic resource of macromolecular complexes from a number of key model organisms, entered into the IntAct molecular interaction database (https://www.ebi.ac.uk/intact/). Data includes protein-only complexes as well as protein-small molecule and protein-nucleic acid complexes. All complexes are derived from physical molecular interaction evidences extracted from the literature and cross-referenced in the entry, or by curator inference from information on homologs in closely related species or by inference from scientific background. All complexes are tagged with Evidence and Conclusion Ontology codes to indicate the type of evidence available for each entry.
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The China National GeneBank database (CNGBdb) is a unified platform for biological big data sharing and application services. CNGBdb has now integrated a large amount of internal and external biological data from resources such as CNGB, NCBI, and the EBI. There are several sub-databases in CNGBdb, including literature, variation, gene, genome, protein, sequence, organism, project, sample, experiment, run, and assembly. Based on underlying big data and cloud computing technologies, it provides various data services, including archive, analysis, knowledge search, and management authorization of biological data. CNGBdb adopts data structures and standards of international omics, health, and medicine, such as The International Nucleotide Sequence Database Collaboration (INSDC), The Global Alliance for Genomics and Health GA4GH (GA4GH), Global Genome Biodiversity Network (GGBN), American College of Medical Genetics and Genomics (ACMG), and constructs standardized data and structures with wide compatibility. All public data and services provided by CNGBdb are freely available to all users worldwide. CNGB Sequence Archive (CNSA) is the bionomics data repository of CNGBdb. CNGB Sequence Archive (CNSA) is a convenient and efficient archiving system of multi-omics data in life science, which provides archiving services for raw sequencing reads and further analyzed results. CNSA follows the international data standards for omics data, and supports online and batch submission of multiple data types such as Project, Sample, Experiment/Run, Assembly, Variation, Metabolism, Single cell, and Sequence. Moreover, CNSA has achieved the correlation of sample entities, sample information, and analyzed data on some projects. Its data submission service can be used as a supplement to the literature publishing process to support early data sharing.CNGB Sequence Archive (CNSA) is a convenient and efficient archiving system of multi-omics data in the life science of CNGBdb, which provides archiving services for raw sequencing reads and further analyzed results. CNSA follows the international data standards for omics data, and supports online and batch submission of multiple data types such as Project, Sample, Experiment/Run, Assembly, Variation, Metabolism, Single cell, Sequence. Its data submission service can be used as a supplement to the literature publishing process to support early data sharing.
OASIS-3 is the latest release in the Open Access Series of Imaging Studies (OASIS) that aimed at making neuroimaging datasets freely available to the scientific community. By compiling and freely distributing this multi-modal dataset, we hope to facilitate future discoveries in basic and clinical neuroscience. Previously released data for OASIS-Cross-sectional (Marcus et al, 2007) and OASIS-Longitudinal (Marcus et al, 2010) have been utilized for hypothesis driven data analyses, development of neuroanatomical atlases, and development of segmentation algorithms. OASIS-3 is a longitudinal neuroimaging, clinical, cognitive, and biomarker dataset for normal aging and Alzheimer’s Disease. The OASIS datasets hosted by central.xnat.org provide the community with open access to a significant database of neuroimaging and processed imaging data across a broad demographic, cognitive, and genetic spectrum an easily accessible platform for use in neuroimaging, clinical, and cognitive research on normal aging and cognitive decline. All data is available via www.oasis-brains.org.
Welcome to INTERMAGNET - the global network of observatories, monitoring the Earth's magnetic field. At this site you can find data and information from geomagnetic observatories around the world. The INTERMAGNET programme exists to establish a global network of cooperating digital magnetic observatories, adopting modern standard specifications for measuring and recording equipment, in order to facilitate data exchanges and the production of geomagnetic products in close to real time.
<<<!!!<<< The demand for high-value environmental data and information has dramatically increased in recent years. To improve our ability to meet that demand, NOAA’s former three data centers—the National Climatic Data Center, the National Geophysical Data Center, and the National Oceanographic Data Center, which includes the National Coastal Data Development Center—have merged into the National Centers for Environmental Information (NCEI). >>>!!!>>> NCEI is responsible for hosting and providing access to one of the most significant archives on Earth, with comprehensive oceanic, atmospheric, and geophysical data. From the depths of the ocean to the surface of the sun and from million-year-old sediment records to near real-time satellite images, NCEI is the Nation's leading authority for environmental information. The National Centers for Environmental Information (NCEI), which hosts the World Data Service for Oceanography is a national environmental data center operated by the National Oceanic and Atmospheric Administration (NOAA) of the U.S. Department of Commerce. NCEI are responsible for hosting and providing access to one of the most significant archives on earth, with comprehensive oceanic, atmospheric, and geophysical data. The primary mission of the World Data Service for Oceanography is to ensure that global oceanographic datasets collected at great cost are maintained in a permanent archive that is easily and openly accessible to the world science community and to other users.
Paleoclimatology data are derived from natural sources such as tree rings, ice cores, corals, and ocean and lake sediments. These proxy climate data extend the archive of weather and climate information hundreds to millions of years. The data include geophysical or biological measurement time series and some reconstructed climate variables such as temperature and precipitation. NCEI provides the paleoclimatology data and information scientists need to understand natural climate variability and future climate change. We also operate the World Data Center for Paleoclimatology, which archives and distributes data contributed by scientists around the world.