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Found 30 result(s)
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VirHostNet is a bioinformatic information system dedidacted to the biocuration, data integration, reproducible systems-level analysis and visualisation of Virus / Host protein-protein interactions Network based on graph theory. VirHostNet is an open and gold standard knowledgebase shared in PSI MITAB 2.5 format using the PSICQUIC webservice and distributed through the NDEx platform. VirHostNet is FAIR and is recognized as a COVID-19 ressource by Elixir bio.tools, the European Virus Bioinformatics Center and FAIRsharing.org.
Stanford Network Analysis Platform (SNAP) is a general purpose network analysis and graph mining library. It is written in C++ and easily scales to massive networks with hundreds of millions of nodes, and billions of edges. It efficiently manipulates large graphs, calculates structural properties, generates regular and random graphs, and supports attributes on nodes and edges. SNAP is also available through the NodeXL which is a graphical front-end that integrates network analysis into Microsoft Office and Excel. The SNAP library is being actively developed since 2004 and is organically growing as a result of our research pursuits in analysis of large social and information networks. Largest network we analyzed so far using the library was the Microsoft Instant Messenger network from 2006 with 240 million nodes and 1.3 billion edges. The datasets available on the website were mostly collected (scraped) for the purposes of our research. The website was launched in July 2009.
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Launched in February 2020, data.sciencespo is a repository that offers visibility, sharing and preservation of data collected, curated and processed at Sciences Po. The repository is based on the Dataverse open-source software and organised into collections: CDSP Collection This collection managed by the Centre des données socio-politiques (CDSP) includes the catalogue of surveys, in the social science and humanities, processed and curated by CDSP engineers since 2005. This catalogue brings together surveys produced at Sciences Po and other French and international institutions. - Sciences Po collection (self-deposit) This collection, which is managed by the Direction des ressources et de l'information scientifique (DRIS), is intended to host data produced by researchers affiliated with Sciences Po, following the self-deposit process assisted by the Library's staff.
The IMPC is a confederation of international mouse phenotyping projects working towards the agreed goals of the consortium: To undertake the phenotyping of 20,000 mouse mutants over a ten year period, providing the first functional annotation of a mammalian genome. Maintain and expand a world-wide consortium of institutions with capacity and expertise to produce germ line transmission of targeted knockout mutations in embryonic stem cells for 20,000 known and predicted mouse genes. Test each mutant mouse line through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human disease. Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems; Maintain and expand collaborative “networks” with specialist phenotyping consortia or laboratories, providing standardized secondary level phenotyping that enriches the primary dataset, and end-user, project specific tertiary level phenotyping that adds value to the mammalian gene functional annotation and fosters hypothesis driven research; and Provide a centralized data centre and portal for free, unrestricted access to primary and secondary data by the scientific community, promoting sharing of data, genotype-phenotype annotation, standard operating protocols, and the development of open source data analysis tools. Members of the IMPC may include research centers, funding organizations and corporations.
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The arctic data archive system (ADS) collects observation data and modeling products obtained by various Japanese research projects and gives researchers to access the results. By centrally managing a wide variety of Arctic observation data, we promote the use of data across multiple disciplines. Researchers use these integrated databases to clarify the mechanisms of environmental change in the atmosphere, ocean, land-surface and cryosphere. That ADS will be provide an opportunity of collaboration between modelers and field scientists, can be expected.
GLOBE (Global Collaboration Engine) is an online collaborative environment that enables land change researchers to share, compare and integrate local and regional studies with global data to assess the global relevance of their work.
<<<!!!<<< As of June 30, 2017, HardinMD has been retired, although it is still findable through the WayBack Machine >>>!!!>>>
Candida Genome Database, a resource for genomic sequence data and gene and protein information for Candida albicans and related species. CGD is based on the Saccharomyces Genome Database. The Candida Genome Database (CGD) provides online access to genomic sequence data and manually curated functional information about genes and proteins of the human pathogen Candida albicans and related species. C. albicans is the best studied of the human fungal pathogens. It is a common commensal organism of healthy individuals, but can cause debilitating mucosal infections and life-threatening systemic infections, especially in immunocompromised patients. C. albicans also serves as a model organism for the study of other fungal pathogens.
The JPL Tropical Cyclone Information System (TCIS) was developed to support hurricane research. There are three components to TCIS; a global archive of multi-satellite hurricane observations 1999-2010 (Tropical Cyclone Data Archive), North Atlantic Hurricane Watch and ASA Convective Processes Experiment (CPEX) aircraft campaign. Together, data and visualizations from the real time system and data archive can be used to study hurricane process, validate and improve models, and assist in developing new algorithms and data assimilation techniques.
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ISIDORE is a international search engine and a discovery platform for open science allowing the access to digital materials from social sciences and humanities (SSH). Open to all and especially to teachers, researchers, PhD students, and students, it relies on the principles of Web of data and provides access to data in free access (open access). By its vocation, ISIDORE will foster access to open access data produced by research and higher education institutions, laboratories and research teams: digital publication, documentary databases, digitized collections of research libraries, research notebooks and scientific event announcements. ISIDORE collects, enriches and highlights digital data and documents from the Humanities and Social Sciences while providing unified access to them. More information see: https://isidore.science/about
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GESIS preserves (mainly quantitative) social research data to make it available to the scientific research community. The data is described in a standardized way, secured for the long term, provided with a permanent identifier (DOI), and can be easily found and reused through browser-optimized catalogs (https://search.gesis.org/).
The CONP portal is a web interface for the Canadian Open Neuroscience Platform (CONP) to facilitate open science in the neuroscience community. CONP simplifies global researcher access and sharing of datasets and tools. The portal internalizes the cycle of a typical research project: starting with data acquisition, followed by processing using already existing/published tools, and ultimately publication of the obtained results including a link to the original dataset. From more information on CONP, please visit https://conp.ca
The Berman Jewish Databank @ The Jewish Federations of North America is the central online address for quantitative studies of North American Jews and Jewish communities. Archives and makes available electronically questionnaires, reports and data files from the National Jewish Population Surveys (NJPS) of 1971, 1990 and 2000-01. It provides access to other national Jewish population reports, Jewish population statistics and approximately 200 local Jewish community studies from the major Jewish communities in North America.
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ConsensusPathDB integrates interaction networks in humans (and in the model organisms - yeast and mouse) including binary and complex protein-protein, genetic, metabolic, signaling, gene regulatory and drug-target interactions, as well as biochemical pathways. Data originate from public resources for interactions and interactions curated from the literature. The interaction data are integrated in a complementary manner to avoid redundancies.
BioModels is a repository of mathematical models of biological and biomedical systems. It hosts a vast selection of existing literature-based physiologically and pharmaceutically relevant mechanistic models in standard formats. Our mission is to provide the systems modelling community with reproducible, high-quality, freely-accessible models published in the scientific literature.
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CEEHRC represents a multi-stage funding commitment by the Canadian Institutes of Health Research (CIHR) and multiple Canadian and international partners. The overall aim is to position Canada at the forefront of international efforts to translate new discoveries in the field of epigenetics into improved human health. The two sites will focus on sequencing human reference epigenomes and developing new technologies and protocols; they will also serve as platforms for other CEEHRC funding initiatives, such as catalyst and team grants. The complementary reference epigenome mapping efforts of the two sites will focus on a range of common human diseases. The Vancouver group will focus on the role of epigenetics in the development of cancer, including lymphoma and cancers of the ovary, colon, breast, and thyroid. The Montreal team will focus on autoimmune / inflammatory, cardio-metabolic, and neuropsychiatric diseases, using studies of identical twins as well as animal models of human disease.
The Substance Abuse and Mental Health Data Archive (SAMHDA) is an initiative funded under contract HHSS283201500001C with the Center for Behavioral Health Statistics and Quality (CBHSQ), Substance Abuse and Mental Health Services Administration (SAMHSA), U.S. Department of Health and Human Services (HHS). CBHSQ has primary responsibility for the collection, analysis, and dissemination of SAMHSA's behavioral health data. Public use files and restricted use files are provided. CBHSQ promotes the access and use of the nation's substance abuse and mental health data through SAMHDA. SAMHDA provides public-use data files, file documentation, and access to restricted-use data files to support a better understanding of this critical area of public health.
<<<!!!<<< The NCBI BioSystems Database will be retired in March 2022. >>>!!!>>> This retirement includes the representation of BioSystems records in the NCBI Entrez system and viewers of BioSystems content. NCBI now provides metabolic pathway and other biosystems data through the regularly updated PubChem Pathways resource (https://pubchemdocs.ncbi.nlm.nih.gov/pathways) that offers a fresh, extended, and more modern interface.
DEPOD - the human DEPhOsphorylation Database (version 1.1) is a manually curated database collecting human active phosphatases, their experimentally verified protein and non-protein substrates and dephosphorylation site information, and pathways in which they are involved. It also provides links to popular kinase databases and protein-protein interaction databases for these phosphatases and substrates. DEPOD aims to be a valuable resource for studying human phosphatases and their substrate specificities and molecular mechanisms; phosphatase-targeted drug discovery and development; connecting phosphatases with kinases through their common substrates; completing the human phosphorylation/dephosphorylation network.
The Solar Dynamics Observatory (SDO) studies the solar atmosphere on small scales of space and time, in multiple wavelengths. This is a searchable database of all SDO data, including citizen scientist images, space weather and near real time data, and helioseismology data.
The NDEx Project provides an open-source framework where scientists and organizations can share, store, manipulate, and publish biological network knowledge. The NDEx Project maintains a free, public website; alternatively, users can also decide to run their own copies of the NDEx Server software in cases where the stored networks must be kept in a highly secure environment (such as for HIPAA compliance) or where high application load is incompatible with a shared public resource.
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APID Interactomes is a database that provides a comprehensive collection of protein interactomes for more than 400 organisms based in the integration of known experimentally validated protein-protein physical interactions (PPIs). Construction of the interactomes is done with a methodological approach to report quality levels and coverage over the proteomes for each organism included. In this way, APID provides interactomes from specific organisms that in 25 cases have more than 500 proteins. As a whole APID includes a comprehensive compendium of 90,379 distinct proteins and 678,441 singular interactions. The analytical and integrative effort done in APID unifies PPIs from primary databases of molecular interactions (BIND, BioGRID, DIP, HPRD, IntAct, MINT) and also from experimentally resolved 3D structures (PDB) where more than two distinct proteins have been identified. In this way, 8,388 structures have been analyzed to find specific protein-protein interactions reported with details of their molecular interfaces. APID also includes a new data visualization web-tool that allows the construction of sub-interactomes using query lists of proteins of interest and the visual exploration of the corresponding networks, including an interactive selection of the properties of the interactions (i.e. the reliability of the "edges" in the network) and an interactive mapping of the functional environment of the proteins (i.e. the functional annotations of the "nodes" in the network).