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Found 27 result(s)
The International Union of Basic and Clinical Pharmacology (IUPHAR) / British Pharmacological Society (BPS) Guide to PHARMACOLOGY is an expert-curated resource of ligand-activity-target relationships, the majority of which come from high-quality pharmacological and medicinal chemistry literature. It is intended as a “one-stop shop” portal to pharmacological information and its main aim is to provide a searchable database with quantitative information on drug targets and the prescription medicines and experimental drugs that act on them. In future versions we plan to add resources for education and training in pharmacological principles and techniques along with research guidelines and overviews of key topics. We hope that the IUPHAR/BPS Guide to PHARMACOLOGY (abbreviated as GtoPdb) will be useful for researchers and students in pharmacology and drug discovery and provide the general public with accurate information on the basic science underlying drug action.
The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data. The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc).
Virtual Fly Brain (VFB) - an interactive tool for neurobiologists to explore the detailed neuroanatomy, neuron connectivity and gene expression of the Drosophila melanogaster CNS.
The GWAS Catalog is an open access repository of all human genome wide association studies. It is considered the “go-to” resource for genetic evidence of associations between common genetic variation and diseases or phenotypes, is accessed by scientists, clinicians and other users worldwide, and is integrated with numerous other resources. Association data and metadata are identified and extracted from the scientific literature by expert data curators. Submissions of full genome wide summary data can be made directly by authors, either before or after journal publication.
This site offers an enormous collection of photographs of wild species and natural history objects. It covers most groups of organisms with the exception of birds and other vertebrates. The photographs are presented to illustrate biodiversity and as an aid to identification. The criterion for inclusion of a species is that it must have been, or might be expected to be, found in Britain or Ireland. BioImages follows the biological classification. Biota is a hierarchical system with species grouped in genera, genera in families, families in orders and so on up to kingdoms and superkingdoms. The datasets are linked to bioinfo: food webs and species interactions in the Biodiversity of UK and Ireland.
The Energy Data Centre holds information relating to energy research, focused on the UK. It has a research data catalogue, information on publications resulting from the UK Energy Research Centre and the Energy Technologies Institute and energy research related grants.
GENCODE is a scientific project in genome research and part of the ENCODE (ENCyclopedia Of DNA Elements) scale-up project. The GENCODE consortium was initially formed as part of the pilot phase of the ENCODE project to identify and map all protein-coding genes within the ENCODE regions (approx. 1% of Human genome). Given the initial success of the project, GENCODE now aims to build an “Encyclopedia of genes and genes variants” by identifying all gene features in the human and mouse genome using a combination of computational analysis, manual annotation, and experimental validation, and annotating all evidence-based gene features in the entire human genome at a high accuracy.
VectorBase provides data on arthropod vectors of human pathogens. Sequence data, gene expression data, images, population data, and insecticide resistance data for arthropod vectors are available for download. VectorBase also offers genome browser, gene expression and microarray repository, and BLAST searches for all VectorBase genomes. VectorBase Genomes include Aedes aegypti, Anopheles gambiae, Culex quinquefasciatus, Ixodes scapularis, Pediculus humanus, Rhodnius prolixus. VectorBase is one the Bioinformatics Resource Centers (BRC) projects which is funded by National Institute of Allergy and Infectious Diseases (NAID).
Science Photo Library (SPL) provides creative professionals with striking specialist imagery, unrivalled in quality, accuracy and depth of information. We have more than 600,000 images and 40,000 clips to choose from, with hundreds of new submissions uploaded to the website each week.
The European Variation Archive is an open-access database of all types of genetic variation data from all species. The EVA provides access to highly detailed, granular, raw variant data from human, with other species to follow. As of September 2017, EMBL-EBI will maintain reliable accessions for non-human genetic variation data through the European Variation Archive (EVA). NCBI's dbSNP database will continue to maintain stable identifiers for human genetic variation data only. This change will enable a more rapid turnaround for data sharing in this burgeoning field.
The Agricultural and Environmental Data Archive (AEDA) is the direct result of a project managed by the Freshwater Biological Association in partnership with the Centre for e-Research at King's College London, and funded by the Department for the Environment, Food & Rural Affairs (Defra). This project ran from January 2011 until December 2014 and was called the DTC Archive Project, because it was initially related to the Demonstration Test Catchments Platform developed by Defra. The archive was also designed to hold data from the GHG R&D Platform (www.ghgplatform.org.uk). After the DTC Archive Project was completed the finished archive was renamed as AEDA to reflect it's broader remit to archive data from any and all agricultural and environmental research activities.
As 3D and reality capture strategies for heritage documentation become more widespread and available, there has emerged a growing need to assist with guiding and facilitating accessibility to data, while maintaining scientific rigor, cultural and ethical sensitivity, discoverability, and archival standards. In response to these areas of need, The Open Heritage 3D Alliance (OHA) has developed as an advisory group governing the Open Heritage 3D initiative. This collaborative advisory group are among some of the earliest adopters of 3D heritage documentation technologies, and offer first-hand guidance for best practices in data management, sharing, and dissemination approaches for 3D cultural heritage projects. The founding members of the OHA, consist of experts and organizational leaders from CyArk, Historic Environment Scotland, and the University of South Florida Libraries, who together have significant repositories of legacy and on-going 3D research and documentation projects. These groups offer unique insight into not only the best practices for 3D data capture and sharing, but also have come together around concerns dealing with standards, formats, approach, ethics, and archive commitment. Together, the OHA has begun the journey to provide open access to cultural heritage 3D data, while maintaining integrity, security, and standards relating to discoverable dissemination. Together, the OHA will work to provide democratized access to primary heritage 3D data submitted from donors and organizations, and will help to facilitate an operation platform, archive, and organization of resources into the future.
MicrosporidiaDB belongs to the EuPathDB family of databases and is an integrated genomic and functional genomic database for the phylum Microsporidia. In its first iteration (released in early 2010), MicrosporidiaDB contains the genomes of two Encephalitozoon species (see below). MicrosporidiaDB integrates whole genome sequence and annotation and will rapidly expand to include experimental data and environmental isolate sequences provided by community researchers. The database includes supplemental bioinformatics analyses and a web interface for data-mining.
ArrayExpress is one of the major international repositories for high-throughput functional genomics data from both microarray and high-throughput sequencing studies, many of which are supported by peer-reviewed publications. Data sets are submitted directly to ArrayExpress and curated by a team of specialist biological curators. In the past (until 2018) datasets from the NCBI Gene Expression Omnibus database were imported on a weekly basis. Data is collected to MIAME and MINSEQE standards.
Codex Sinaiticus is one of the most important books in the world. Handwritten well over 1600 years ago, the manuscript contains the Christian Bible in Greek, including the oldest complete copy of the New Testament. The Codex Sinaiticus Project is an international collaboration to reunite the entire manuscript in digital form and make it accessible to a global audience for the first time. Drawing on the expertise of leading scholars, conservators and curators, the Project gives everyone the opportunity to connect directly with this famous manuscript.
The Electron Microscopy Data Bank (EMDB) is a public repository for electron microscopy density maps of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, electron tomography, and electron (2D) crystallography.
PHI-base is a web-accessible database that catalogues experimentally verified pathogenicity, virulence and effector genes from fungal, Oomycete and bacterial pathogens, which infect animal, plant, fungal and insect hosts. PHI-base is therfore an invaluable resource in the discovery of genes in medically and agronomically important pathogens, which may be potential targets for chemical intervention. In collaboration with the FRAC team, PHI-base also includes antifungal compounds and their target genes.
Content type(s)
The British Ocean Sediment Core Research Facility (BOSCORF) is based at the Southampton site of the National Oceanography Centre and is Britain’s national deep-sea core repository. BOSCORF is responsible for long-term storage and curation of sediment cores collected through UKRI-NERC research programmes. We promote secondary usage of sediment core samples and analytical data relating to the sample collection.
EuPathDB (formerly ApiDB) is an integrated database covering the eukaryotic pathogens in the genera Acanthamoeba, Annacaliia, Babesia, Crithidia, Cryptosporidium, Edhazardia, Eimeria, Encephalitozoon, Endotrypanum, Entamoeba, Enterocytozoon, Giardia, Gregarina, Hamiltosporidium, Leishmania, Nematocida, Neospora, Nosema, Plasmodium, Theileria, Toxoplasma, Trichomonas, Trypanosoma and Vavraia, Vittaforma). While each of these groups is supported by a taxon-specific database built upon the same infrastructure, the EuPathDB portal offers an entry point to all of these resources, and the opportunity to leverage orthology for searches across genera.
Content type(s)
A genome database for the genus Piroplasma. PiroplasmaDB is a member of pathogen-databases that are housed under the NIAID-funded EuPathDB Bioinformatics Resource Center (BRC) umbrella.
The ADS is an accredited digital repository for heritage data that supports research, learning and teaching with freely available, high quality and dependable digital resources by preserving and disseminating digital data in the long term. The ADS also promotes good practice in the use of digital data, provides technical advice to the heritage community, and supports the deployment of digital technologies.
This data repository contains the experimental data produced at the ISIS Neutron and Muon Source (https://www.isis.stfc.ac.uk/Pages/home.aspx/) in the UK Science and Technology Facilities Council (STFC, https://www.ukri.org/councils/stfc/). The repository contains the open data as well as the data under embargoed that can be accessed by the data producers.
DIAMM (the Digital Image Archive of Medieval Music) is a leading resource for the study of medieval manuscripts. We present images and metadata for thousands of manuscripts on this website. We also provide a home for scholarly resources and editions, undertake digital restoration of damaged manuscripts and documents, publish high-quality facsimiles, and offer our expertise as consultants.
Apollo (previously DSpace@Cambridge) is the University of Cambridge’s Institutional Repository (IR), preserving and providing access to content created by members of the University. The repository stores a range of content and provides different levels of access, but its primary focus is on providing open access to the University’s research publications.
Content type(s)
TrichDB integrated genomic resources for the eukaryotic protist pathogens Trichomonas vaginalis.